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propionaldehyde (propanal)

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may cause respiratory irritation; RN given refers to parent cpd; structure

Also Known As:

propanal; propionaldehyde, 1-14C-labeled; propionaldehyde, 2-14C-labeled

Networked: 19 relevant articles (0 outcomes, 1 trials/studies) for this Bio-Agent, Comments

Bio-Agent Context: Research Results

Organic Chemicals: 45
- Aldehydes: 354
  - propionaldehyde: 19

Experts

1.	Vasconcelos, J B: 1 article (06/2010)
2.	Valença, J T: 1 article (06/2010)
3.	Schubert, Jochen K: 1 article (06/2010)
4.	Miekisch, Wolfram: 1 article (06/2010)
5.	Meija, J A: 1 article (06/2010)
6.	Marques, G A: 1 article (06/2010)
7.	Loeseken, Christian: 1 article (06/2010)
8.	Leite, C A: 1 article (06/2010)
9.	Garcia, J H: 1 article (06/2010)
10.	Gadelha, J B: 1 article (06/2010)

Related Diseases

1.	Cataract (Cataracts) 08/01/1983 - "From studies involving 31 cataracts classified by the CCRG system and eight normal human lenses, it has been found that the adult human lens contains an enzyme system capable of oxidizing 1-2 mumol of glyceraldehyde, acetaldehyde, propionaldehyde, formaldehyde, and malonaldialdehyde per hour to their carboxylic acid form. " Order ALL the reference details at left...
2.	Neoplasms (Cancer) 06/01/1987 - "Over a period of 350 days, animals were killed at intervals and the ALDH phenotype of normal liver and any lesions was characterized by histochemical analysis, total activity assays and gel electrophoresis using propionaldehyde and NAD+ to detect normal liver ALDH activities, and benzaldehyde and NADP+ for tumor-associated ALDH. " 08/25/1992 - "There was no detectable aldehyde dehydrogenase activity in the extract of the prostate with cancer on IEF gels nor in the activity assays with propionaldehyde or gamma-aminobutyraldehyde as substrates." 07/01/1986 - "Over a period of 43 weeks, animals were sacrificed at intervals and the ALDH phenotype of normal liver and any lesions was characterized by histochemical analysis, total activity assays, and gel electrophoresis, using propionaldehyde and nicotinamide adenine dinucleotide (NAD+) to detect normal liver ALDH activity and benzaldehyde and nicotinamide adenine dinucleotide phosphate (NADP+) for tumor-associated ALDH. " 12/01/1984 - "The hepatic ALDH phenotype was determined at intervals over 280 days by histochemical analysis, total ALDH activity assays and gel electrophoresis, using propionaldehyde and NAD (P/NAD) to characterize normal liver ALDH activity or benzaldehyde and NADP (B/NADP) to determine tumor-associated ALDH activity. " 12/01/1983 - "Neoplasms with elevated ALDH activity with propionaldehyde-NAD and/or benzaldehyde-NADP, as well as with no detectable ALDH, have been observed. " Order ALL the reference details at left...
3.	Hepatocellular Carcinoma (Hepatoma) 01/30/2001 - "Four hours after treatment with 25 microM ATEM, ALDH activity using benzaldehyde or propionaldehyde in hepatoma cells was decreased by 40% and cell number by 15% compared with controls. " 08/01/1997 - "The metabolism of acetaldehyde (ACA), benzaldehyde (BA), propionaldehyde (PA) and valeraldehyde (VA) has been studied in two hepatoma cell lines, the rat HTC and mouse Hepa 1c1c7 cells. " 12/01/1985 - "The activities of propionaldehyde:NAD and benzaldehyde:NADP aldehyde dehydrogenases were increased in hepatocyte nodules of all types as well as in most hepatocellular carcinomas. " 12/01/1985 - "The activities of aldehyde dehydrogenases using benzaldehyde and propionaldehyde as substrates and NADP and NAD as coenzymes were determined in normal liver, hepatocyte nodules and hepatocellular carcinomas from male Wistar rats. " Order ALL the reference details at left...
4.	DNA Damage 04/01/2008 - "We propose that a primary function of the MCPs involved in 1,2-PD degradation is the mitigation of toxicity and DNA damage by propionaldehyde." 03/01/1995 - "We have therefore examined the chronic effects of sodium dichromate dihydrate [Cr(VI); 10 mg (33.56 mumol)/kg/day] on hepatic mitochondrial and microsomal lipid peroxidation, enhanced excretion of urinary lipid metabolites including malondialdehyde (MDA), formaldehyde (FA), acetaldehyde (ACT), acetone (ACON) and propionaldehyde (PROP), and hepatic DNA damage over a period of 90 days. " Order ALL the reference details at left...
5.	Sjogren-Larsson Syndrome 11/01/1991 - "The extent of FALDH deficiency in SLS cells depended on the aliphatic aldehyde used as substrate, ranging from 62% of mean normal activity using propionaldehyde as substrate to 8% of mean normal activity with octadecanal. " Order ALL the reference details at left...

Related Drugs and Biologics

1.	Acetaldehyde
2.	Formaldehyde (Formol)
3.	Glyceraldehyde
4.	benzaldehyde
5.	NAD (NADH)
6.	NADP (NADPH)
7.	Aldicarb (Temik)
8.	Ethylene Dibromide (1,2 Dibromoethane)
9.	Oxidoreductases
10.	Methionine (L-Methionine)

Related Therapies and Procedures

1.	Lenses
2.	Cardiopulmonary Resuscitation (CPR)
3.	Heart Transplantation (Grafting, Heart)
4.	Aftercare (After-Treatment)

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