|1.||Kim, Yeong Shik: 2 articles (01/2010 - 08/2009)|
|2.||Xie, Jianping: 1 article (10/2015)|
|3.||Hambright, Heather G: 1 article (10/2015)|
|4.||Kumar, Addanki Pratap: 1 article (10/2015)|
|5.||Batth, Izhar Singh: 1 article (10/2015)|
|6.||Ghosh, Rita: 1 article (10/2015)|
|7.||Wang, Yanzhi: 1 article (05/2015)|
|8.||Li, Xuegang: 1 article (05/2015)|
|9.||He, Kai: 1 article (05/2015)|
|10.||Wu, Hao: 1 article (05/2015)|
08/01/2009 - "Palmatine from Coptidis rhizoma reduces ischemia-reperfusion-mediated acute myocardial injury in the rat."
01/01/2010 - "The anti-ischemia effect in myocardium of Rhizoma Corydalis is related to the direct protective effects on cardiomyocytes of its components, tetrahydropalmatine, dehydrocorydaline, berberine and palmatine, amomg which tetrahydropalmatine and dehydrocorydaline are the most important, the former with high safety and low efficacy, while the latter with low safety and high efficacy. "
01/01/2010 - "To observe the effects of tetrahydropalmatine, dehydrocorydaline, berberine and palmatine on anoxia and peroxidation injuries in cardiomyocytes, and study the marterial basis of the anti-ischemia effect on myocardium of Rhizoma Corydalis. "
|2.||Phototoxic Dermatitis (Phototoxicity)
06/01/2006 - "Although palmatine is photoactive, it is present in such small amounts in Goldenseal root powder that the phototoxicity of the herb is most likely due to berberine, the major constituent alkaloid."
10/01/2005 - "The present study suggests that berberine and palmatine can act as functional photosensitizers enabling a switch in phototoxicity via 1O2 formation by the interaction with DNA."
07/01/2007 - "Berberine and palmatine are the only Goldenseal alkaloids with appreciable absorption above 400 nm. Because light at wavelengths below 400 nm is cut off by the anterior portion of the adult human eye only berberine and palmatine were tested for phototoxicity to human retinal pigment epithelial (hRPE) cells. "
01/01/2007 - "Palmatine is an isoquinoline alkaloid that has been widely used in China for the treatment of various inflammatory diseases such as gynecological inflammation, bacillary dysentery, enteritis, respiratory tract infection, urinary infection, etc. In the study reported in this paper, a simple and rapid high-performance liquid chromatography/electrospray ionization (ESI) tandem mass spectrometric method (MS/MS) was developed for elucidation of the structures of metabolites of palmatine in rat urine after administration of a single dose (20 mg/kg). "
12/27/2002 - "All alkaloids inhibited inflammations in varying degrees, among them berberine, berbamine and palmatine were shown to possess significant and dose-dependent inhibitory activity against serotonin-induced hind paw oedema both on oral and topical applications and acetic acid-induced increase in vascular permeability on oral administration. "
|4.||Hepatocellular Carcinoma (Hepatoma)
06/01/2014 - "This study examined whether palmatine affects the expression of cytochromes P450 (CYPs) 1A1 and 1A2 in primary cultures of human hepatocytes and human hepatoma HepG2 cells grown as monolayer or spheroids. "
07/31/2013 - "As measured by the Comet assay and the expression of γ-H2A.X, berberine, followed by palmatine, appeared to be the most potent DNA damage inducer in human hepatoma HepG2 cells. "
|5.||Irritable Bowel Syndrome (Syndrome, Irritable Bowel)
01/01/2014 - "A comparative pharmacokinetic study of berberine and palmatine after oral administration of Rhizoma Coptidis extract (96 mg/kg, containing berberine 22 mg/kg and palmatine 5 mg/kg based on body weight) was performed in normal and postinflammation irritable bowel syndrome (PI-IBS) rats, induced by intracolonic instillation of acetic acid and restraint stress. "
|4.||Acetic Acid (Vinegar)
|5.||DNA (Deoxyribonucleic Acid)
|7.||Photosensitizing Agents (Photosensitizers)
|2.||Traditional Medicine (Folk Remedies)