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nybomycin

antibiotic substance produced by Streptomyces A 717; structure

Also Known As:

8,9-dihydro-4-(hydroxymethyl)-6,9-dimethyl-2,8- dioxopyrido(3,2-g)quinoline-1(2H)-carboxaldehyde

Networked: 2 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Quinolines: 146
      - Quinolones: 2938
        nybomycin: 2

Experts

1.	Copley, Gregory C: 1 article (12/2019)
2.	Elshahawi, Sherif I: 1 article (12/2019)
3.	Hatcher, Bruce E: 1 article (12/2019)
4.	Hower, James C: 1 article (12/2019)
5.	Kharel, Madan K: 1 article (12/2019)
6.	Liu, Yang: 1 article (12/2019)
7.	Ponomareva, Larissa V: 1 article (12/2019)
8.	Shaaban, Khaled A: 1 article (12/2019)
9.	She, Qing-Bai: 1 article (12/2019)
10.	Thorson, Jon S: 1 article (12/2019)

Related Diseases

1.	Infections 04/24/2015 - "Using a DNM derivative, the first in-vivo efficacy of the nybomycin class is demonstrated in a mouse infection model. "
2.	Neoplasms (Cancer) 12/27/2019 - "Nybomycin D (3) and deoxynyboquinone (5) displayed moderate (3) to potent (5) cancer cell line cytotoxicity and displayed weak to moderate anti-Gram-(+) bacterial activity, whereas rubromycins 6-8 displayed little to no cancer cell line cytotoxicity but moderate to potent anti-Gram-(+) bacterial and antifungal activity. "

Related Drugs and Biologics

1.	deoxynyboquinone