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myxin

structure

Also Known As:

1-hydroxy-6-methoxyphenazine-5,10-dioxide

Networked: 6 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 3-Ring Heterocyclic Compounds
    - Phenazines: 42
      - myxin: 6

Experts

1.	Aesoy, Reidun: 2 articles (04/2021 - 01/2017)
2.	Døskeland, Stein Ove: 2 articles (04/2021 - 01/2017)
3.	Herfindal, Lars: 2 articles (04/2021 - 01/2017)
4.	Rongved, Pål: 2 articles (04/2021 - 01/2017)
5.	Viktorsson, Elvar Örn: 2 articles (04/2021 - 01/2017)
6.	Fu, Zheng Qing: 1 article (11/2021)
7.	Liu, Fengquan: 1 article (11/2021)
8.	Liu, Jiayu: 1 article (11/2021)
9.	Zhao, Yangyang: 1 article (11/2021)
10.	Lekve, Viola: 1 article (04/2021)

Related Diseases

1.	Neoplasms (Cancer) 11/17/2021 - "Myxin, a di-N-oxide phenazine produced by Lysobacter antibioticus OH13, is toxic to many microorganisms and tumor cells. " 01/01/2017 - "Analogues prepared from iodinin, including myxin and 2-ethoxy-2-oxoethoxy derivatives, had fully retained cytotoxic effect against human cancer cells (MOLM-13 leukemia) at atmospheric and low oxygen level. "
2.	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 04/19/2021 - "New prodrugs and analogs of the phenazine 5,10-dioxide natural products iodinin and myxin promote selective cytotoxicity towards human acute myeloid leukemia cells."
3.	Colorectal Neoplasms (Colorectal Cancer) 01/13/2012 - "We show that myxin displays potent cytotoxicity against the human colorectal cancer cell line HCT-116 under both aerobic and anaerobic conditions that is comparable to the cell-killing properties of tirapazamine under anaerobic conditions. "
4.	Tinea (Ringworm) 05/01/1968 - "Chemotherapeutic activity of myxin in experimental dermatophytosis of guinea pigs."
5.	Infections 03/01/1971 - "After exposure to myxin for 30 min (<1% survivors and >25% degradation of DNA), infection of these cells by T4 bacteriophage results in the renewal of DNA synthesis at a rate essentially equal to that found in T4-infected cells in the absence of myxin. "

Related Drugs and Biologics

1.	Oxides
2.	iodinin
3.	Prodrugs
4.	Oxygen (Dioxygen)
5.	DNA (Deoxyribonucleic Acid)
6.	Tirapazamine (SR 4233)
7.	phenazine di-N-oxide
8.	phenazine