myristicin

10/07/2022 - "The present study aimed to evaluate the effect of the association between myristicin and chemotherapeutic agents on the NCI/ADR-RES ovarian tumor lineage that presents a phenotype of multidrug resistance by overexpression of P-gp. "
10/01/1992 - "The results of this study indicate that as a major volatile aroma constituent of parsley myristicin may be an effective cancer chemopreventive agent."
10/01/1992 - "A 65% inhibition of the tumor multiplicity in the lung was observed as the result of treatment of myristicin. "
10/07/2022 - "Effects of Myristicin in Association with Chemotherapies on the Reversal of the Multidrug Resistance (MDR) Mechanism in Cancer."
01/01/2023 - "Myristicin exerts an anti-cancer effect on gastric cancer cells by restraining the EGFR/ ERK signaling pathway. "

01/01/2023 - "In this study, the effect of myristicin on gastric cancer as well as its underlying mechanism was investigated. "
01/01/2023 - "Also, myristicin inhibited the growth of gastric cancer cells as well as the EGFR/ERK signaling pathway in vivo. "
01/01/2023 - "On the other hand, the effect of myristicin on gastric cancer growth and apoptosis was also determined in vivo. "
01/01/2023 - "Human gastric cancer cells were exposed to various concentrations of myristicin (0, 7.8125, 15.625, and 31.25 μM) for 48 h. "
01/01/2023 - "Myristicin Suppresses Gastric Cancer Growth via Targeting the EGFR/ ERK Signaling Pathway."

05/16/2005 - "The present study was conducted to assess the cytotoxic and apoptotic effects of myristicin on the human neuroblastoma SK-N-SH cells. "
05/16/2005 - "The results obtained suggest that myristicin induces cytotoxicity in human neuroblastoma SK-N-SH cells by an apoptotic mechanism. "
05/16/2005 - "Myristicin-induced neurotoxicity in human neuroblastoma SK-N-SH cells."

01/01/2013 - "The increasing use of myristicin as a cheap hallucinogenic intoxicant, frequently causing fatal cases of myristicin poisoning, requires new methods for determination of this compound in blood. "
04/15/2001 - "Nutmeg (myristicin) poisoning--report on a fatal case and a series of cases recorded by a poison information centre."
09/20/2023 - "Detection of major psychoactive compounds (safrole, myristicin, and elemicin) of nutmeg in human serum via GC-MS/MS using MonoSpin® extraction: Application in a nutmeg poisoning case."

01/01/1997 - "Several intoxications have been reported after an ingestion of approximately 5 g of nutmeg, corresponding to 1-2 mg myristicin/kg body weight (b.w.). "
12/15/2022 - "Adult male rats were treated with 150 mg/kg body weight of myristicin or mesalazine orally either as pre/post treatment or post-treatment only. "
03/01/2019 - "Male and female F344/NTac rats and B6C3F1/N mice received myristicin (greater than 94% pure) in corn oil by gavage at doses of 0, 10, 30, 100, 300, or 600 mg/kg body weight 5 days per week for 13 weeks. "