N-methyl-4-aminoazobenzene

structure

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

1.	Neoplasms (Cancer) 12/01/1981 - "N-Methyl-4-aminoazobenzene (MAB) is believed to be metabolized in the liver to an electrophilic N-sulfonyloxy ester which binds covalently to cellular macromolecules, resulting in the induction of hepatic neoplasia. " 04/01/1987 - "Chronic oral administration of the carcinogenic aminoazo dye N-methyl-4-aminoazobenzene (MAB) to rats is known to result in the induction of liver tumors. " 07/01/1980 - "Since the susceptibility of specific tissues to tumor formation has been correlated with the persistence of DNA-carcinogen adducts, the identity and persistence of DNA adducts formed from the hepatocarcinogen N-methyl-4-aminoazobenzene (MAB) has been determined. "
2.	Carcinogenesis 07/15/1972 - "Genetic properties of substituted derivatives of N-methyl-4-aminoazobenzene in relation to azo-dye carcinogenesis."
3.	Hepatocellular Carcinoma (Hepatoma) 02/01/1986 - "Under identical conditions, PCP also reduced the average number of hepatomas induced per mouse at 9 months by AB and N-methyl-4-aminoazobenzene (MAB) by 52 and 36%, respectively. "

1.	Oral Administration