|1.||Sayed, Ahmed Amir Radwan: 1 article (01/2013)|
|2.||Al-Malki, Abdulrahman L: 1 article (01/2013)|
|3.||Rao, K V K: 1 article (01/2003)|
|4.||Sundarrajan, Monisha: 1 article (01/2003)|
|5.||Gupta, Sanjay: 1 article (01/2003)|
|6.||Sundarrajan, M: 1 article (07/2000)|
|7.||Prabhudesai, S: 1 article (07/2000)|
|8.||Subrahmanyam, G: 1 article (07/2000)|
|9.||Fernandis, A Z: 1 article (07/2000)|
|10.||Krishnamurthy, S C: 1 article (07/2000)|
|1.||Body Weight (Weight, Body)
04/01/1983 - "Metanil yellow was administered daily in the food at the rate of 0.0, 0.1, 0.5 and 3.0 g/kg body weight for 180 days to male and female albino mice. "
08/01/1997 - "Oral administration of metanil yellow (430 mg/kg body weight) to four animals for seven days caused significant induction of hepatic P-450 (48%) and its dependent aryl hydrocarbon hydroxylase (100%) activity and cytosolic GST (136%) and QR (92%) activities. "
01/01/1992 - "The blend of Metanil yellow and Orange II (40 mg + 40 mg/kg body weight) given intraperitoneally for 3 days resulted in either synergistic or additive effect in nuclear (122%), mitochondrial (130%), and microsomal (62%) membranes. "
01/01/1992 - "Parenteral administration of Metanil yellow (80 mg/kg body weight) to rats for 3 days produced a highly significant (p less than 0.001) increase in NADPH-dependent enzymatic lipid peroxidation in nuclear (62%), mitochondrial (104%) and microsomal (54%) fractions. "
08/01/1997 - "Parenteral administration of metanil yellow (80 mg/kg body weight) to another set of four animals for 3 days resulted in higher induction of ethoxyresorufin-O-deethylase (228%) as compared to other monooxygenases (64-92%), while GST and QR were also found to be induced (59-95%). "
01/01/2003 - "These data obtained by the in vivo model of liver tumor development provide strong evidence for a link between dysregulation of the two critical checkpoints of the cell cycle as one of the possible mechanism(s) during tumor promotion by malachite green and metanil yellow."
01/01/2003 - "Tumor promotion by metanil yellow and malachite green during rat hepatocarcinogenesis is associated with dysregulated expression of cell cycle regulatory proteins."
07/27/2000 - "In order to understand the possible mechanism(s) by which metanil yellow (MY) and malachite green (MG) promotes liver tumor development, we have studied the tyrosine phosphorylation and protein phosphatases during tumor promotion. "
07/27/2000 - "Overexpression of G1/S cyclins and PCNA and their relationship to tyrosine phosphorylation and dephosphorylation during tumor promotion by metanil yellow and malachite green."
|4.||Allergic Contact Dermatitis
08/01/1994 - "A case of allergic contact dermatitis due to metanil yellow."
|5.||Wounds and Injuries (Trauma)
01/01/2013 - "In conclusion, the obtained data suggest that bees' honey has hepatoprotective effect on acute liver injuries induced by metanil-yellow in vivo, and the results suggested that the effect of bees' honey against metanil yellow-induced liver damage is related to its antioxidant/anti-inflammatory properties which attenuate the activation of NF- κ B and its controlled genes like TNF- α and IL-1 β . "
|1.||Cytochrome P-450 CYP1A1 (CYP1A1)
|2.||2-naphthol orange (Orange II)
|4.||Proliferating Cell Nuclear Antigen (PCNA)
|5.||Cell Cycle Proteins
|8.||Phosphoprotein Phosphatases (Phosphatases, Protein)
|10.||Interleukin-1 (Interleukin 1)