alpha-ketobutyric acid

RN given refers to parent cpd; structure

Also Known As:

2-ketobutyrate; 2-ketobutyric acid; 2-oxobutanoate; 2-oxobutyrate; alpha-ketobutyric acid, sodium salt; alpha-oxobutyric acid; 2-oxobutanoic acid

Networked: 6 relevant articles (0 outcomes, 0 trials/studies)

1.	Atherosclerosis 11/23/2023 - "Higher 2-ketobutyric acid and cyclic GMP levels were positively correlated with ACS risk and atherosclerosis plaque burden, while LysoPC(18:2(9Z,12Z)) and argininosuccinic acid showed the reverse relationship. "
2.	Starvation 01/01/1983 - "2-ketobutyrate was shown to inhibit the phosphoenolpyruvate (PEP): sugar phosphotransferase system resulting in aspartate starvation, elevation of ppGpp endogenous pools, and cessation of growth in E. "
3.	Obesity 01/01/2023 - "Additionally, metabolomic analysis suggests that 2-ketobutyrate should be a possible target compound against obesity. "
4.	Hypoglycemia (Reactive Hypoglycemia) 01/01/1969 - "II. The hypoglycemic affect of alpha-ketobutyric acid in the case of "leucine sensitive hypoglycemia"."
5.	Dehydration (Water Stress) 12/01/1994 - "Threonine dehydratase, the first enzyme in isoleucine biosynthesis, catalyzes deamination and dehydration of threonine to produce 2-ketobutyrate and ammonia. "

1.	Pyruvic Acid (Pyruvate)
2.	Threonine Dehydratase (Threonine Ammonia-Lyase)
3.	Threonine (L-Threonine)
4.	Phosphotransferases (Kinase)
5.	Phosphoenolpyruvate
6.	Leucine (L-Leucine)
7.	Isoleucine (L-Isoleucine)
8.	Hypoglycemic Agents (Hypoglycemics)
9.	Guanosine Tetraphosphate
10.	Cyclic GMP