harman (harmane)

12/01/2003 - "Therefore, harmane seems to be protective against grand mal seizures in the MES model but not against a petit mal seizure model (PTZ) in mice."
12/01/2003 - "The study investigated the activity of harmane on maximal electroshock seizures (MES) and seizures induced by pentilentetrazole (PTZ) in mice. "
12/01/2003 - "Harmane (2.5, 5.0, or 10 mg/kg intraperitoneally) increased the threshold of seizures in MES dose-dependently. "
07/02/1981 - "Haloperidol did not influence the effect of TSC; it enhanced isoniazid-induced seizures, and antagonized the convulsant effect of harman."
07/02/1981 - "Caerulein, cholecystokinin octapeptide (CCK-8) and diazepam delayed the onset of seizures produced by harman and thiosemicarbazide (TSC). "

05/23/2022 - "Harmane did not cause adverse effects on the health of rats, whereas acrylamide and CML resulted in significantly (P < 0.05) decreased insulin sensitivity (HOMA-IR > 1), increased oxidative stress levels, and pathological injuries to the pancreas, liver, and gastrocnemius. "
01/01/1996 - "harman and norharman levels, could identify chronic alcoholics following trauma and whether possible changes during ICU stay could serve as a predictor of deterioration of clinical status. "
05/23/2022 - "Owing to the antioxidant and anti-diabetic activities of harmane, the effects of the combination of the MRPs on oxidative stress levels, blood glucose metabolism, and pathological injuries to the pancreas and gastrocnemius were relieved. "

01/24/2020 - "Therefore, harmane ameliorates obesity though inhibiting lipid accumulation and inducing adipocyte browning."
01/24/2020 - "Harmane ameliorates obesity though inhibiting lipid accumulation and inducing adipocyte browning."

01/01/2021 - "Several β-carboline alkaloids (βCBs), such as harmine, harmaline, harmane, and nor-harmane, are effective for Alzheimer's disease mouse models. "

09/15/2008 - "These links between cancer and ET and between high blood harmane and cancer in ET deserve further study."
01/01/2022 - "These data can be evaluated by Peritoneal Cancer Index (PCI), a quantitative index suggested by Harman and Sugarbaker. "
01/01/2016 - "Seven decades ago, a seminal paper by Dr. Denham Harman in (J Gerontol 11(3):298-300, 1956), introduced a theory stating that there are good reasons for assuming that endogenous irradiation in the living cells could lead to cancer via an obscure mechanism. "
09/15/2008 - "Log blood harmane concentration was highest in ET cases with cancer when compared with other groups (P = 0.009). "
09/15/2008 - "Log blood harmane concentration was higher in ET cases vs. controls (P = 0.02) and in participants with vs. without cancer (P = 0.02). "