guanadrel (Hylorel)

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13 relevant articles (2 outcomes, 1 trials/studies) found for this Drug

Description: RN given refers to parent cpd; structure

Also Known As:

Hylorel; guanadrel sulfate; Celltech brand of guanadrel sulfate; (1,4-dioxaspiro(4.5)dec-2-ylmethyl)guanidine

Relationship Network

Drug Context: Research Results

Organic Chemicals: 40

Amidines: 8

Guanidines: 11

guanadrel: 13

Related Diseases

1.	Hypertension (High Blood Pressure) 07/01/1985 - "A dose-titration trial of guanadrel as step-two therapy in essential hypertension." 07/01/1988 - "Our conclusion is that guanadrel is an effective, well-tolerated medication for treatment of hypertension in the elderly." 11/01/1985 - "Addition of guanadrel to diuretic therapy in 11 patients with essential hypertension reduced supine intra-arterial blood pressure from 135 +/- 14/76 +/- 9 to 127 +/- 13/67 +/- 5 mm Hg (P less than 0.02)" 07/01/1983 - "Guanadrel sulfate: a postganglionic sympathetic inhibitor for the treatment of mild to moderate hypertension." 01/01/1983 - "In light of the efficacy without severe side effects, guanadrel may be an agent for step II therapy of hypertension." Get all the results and reference details, order at left...
2.	Dizziness (Lightheadedness) 07/01/1985 - "In comparative studies, guanadrel was comparable in efficacy with guanethidine or methyldopa in mild to moderately severe hypertension, although generally it caused fewer central nervous system side effects than methyldopa and less orthostatic dizziness and diarrhoea than guanethidine" Get all the results and reference details, order at left...
3.	Renal Insufficiency 02/01/1989 - "Thus, the disposition of guanadrel is significantly altered in the presence of renal insufficiency and dosage adjustments may be necessary, especially in patients with ClCr less than 50 ml/min." Get all the results and reference details, order at left...
4.	Thyrotoxicosis 07/01/1978 - "We conclude that guanadrel sulfate may be useful in the symptomatic management of patients with thyrotoxicosis." 07/01/1978 - "Effects of guanadrel on patients with thyrotoxicosis." Get all the results and reference details, order at left...
5.	Graves Disease (Basedow Disease) 07/01/1978 - "Eleven patients with Graves' disease were treated with guanadrel sulfate and observed for changes in neuromuscular and cardiovascular manifestations" Get all the results and reference details, order at left...
7 Diseases and 13 more articles analyzed in the Research Interface, order at left...

Related Drugs and Biologics

1.	Hydrochlorothiazide (Esidrix)
2.	Guanethidine
3.	Propranolol (Inderal)
4.	Methyldopa (Aldomet)
5.	4- chloro- 3',6'- dimethyl- 2,2'- iminodibenzoate (TO 115)
6.	Diuretics
7.	Lipoproteins (Lipoprotein)
8.	Glucose (Dextrose)
8 Drugs and Important Bio-Agents and 7 more articles analyzed in the Research Interface, order at left...

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