coomassie Brilliant Blue

Also Known As:

C.I. 42655; Coomassie brilliant blue G 250; Coomassie brilliant blue G250; acid blue 90; brilliant blue G; coomassie blue G; serva blue G; supranol cyanine G; xylene brilliant cyanine G

Networked: 181 relevant articles (9 outcomes, 21 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Aniline Compounds: 46
    - Rosaniline Dyes: 73
      - coomassie Brilliant Blue: 181

Experts

1.	Wang, Wei: 4 articles (11/2020 - 10/2011)
2.	Enaida, Hiroshi: 4 articles (10/2013 - 07/2006)
3.	Ishibashi, Tatsuro: 4 articles (10/2013 - 07/2006)
4.	Kurosaka, Daijiro: 3 articles (03/2017 - 01/2014)
5.	Machida, Shigeki: 3 articles (03/2017 - 01/2014)
6.	Gandorfer, Arnd: 3 articles (10/2010 - 03/2008)
7.	Haritoglou, Christos: 3 articles (10/2010 - 03/2008)
8.	Schumann, Ricarda G: 3 articles (10/2010 - 03/2008)
9.	Chhablani, Jay: 2 articles (01/2022 - 04/2017)
10.	Castelucci, Patricia: 2 articles (01/2022 - 01/2019)

Related Diseases

1.	Retinal Perforations 01/01/2014 - "SD-OCT analysis of GCIPL thickness found a significant reduction at the temporal macular quadrants at 6 months after Brilliant Blue G-assisted internal limiting membrane peeling for idiopathic macular hole." 10/01/2013 - "The color difference between Brilliant Blue G-stained and nonstained areas was improved by 127.8% relative to values with no filter and using SCY (P < 0.01) in macular hole cases. " 01/01/2019 - "The aim of this study was to determine the functional and anatomical success rates as well as the safety of sutureless combined surgery involving vitreous base removal and internal limiting membrane peeling after Brilliant Blue G (0.5 mg/mL) staining for the management of idiopathic macular holes after three years. " 08/14/2014 - "The staining pattern of brilliant blue G during macular hole surgery: a clinicopathologic study." 11/01/2012 - "A preliminary study of Heavy Brilliant Blue G for internal limiting membrane staining in macular hole surgery."
2.	Neuroinflammatory Diseases 09/30/2021 - "In this context, we previously demonstrated that the P2X7 receptor antagonist, brilliant blue G, reduces neuroinflammation and ameliorates some of the pathological features of ALS in the SOD1-G93A mouse model. " 09/01/2014 - "In order to clarify this dual action of P2X7 in ALS pathogenesis, in the present work we used the antagonist Brilliant Blue G (BBG), a blood-brain barrier permeable and safe drug that has already been proven to reduce neuroinflammation in traumatic brain injury, cerebral ischemia-reperfusion, neuropathic pain and experimental autoimmune encephalitis. " 10/24/2014 - "Brilliant Blue G (BBG), a safe triphenylmethane dye and P2X7 antagonist, has been reported to have protective effects on neuroinflammation, ischemia, spinal injury and neurodegenerative disorders. "
3.	Spinal Cord Injuries (Spinal Cord Injury) 08/24/2019 - "BACKGROUND Brilliant blue G (BBG) is a P2X7 receptor inhibitor that has been reported to improve spinal cord injury (SCI) in previous studies, but the specific mechanism has been unclear. " 08/24/2019 - "Brilliant Blue G Inhibits Inflammasome Activation and Reduces Disruption of Blood-Spinal Cord Barrier Induced by Spinal Cord Injury in Rats." 12/03/2014 - "Previous studies in rats have demonstrated beneficial effects of inhibition of the P2X7 receptor with brilliant blue G (BBG) after spinal cord injury; however, little is known about BBG as a potential treatment strategy for optic nerve injuries. "
4.	Ischemia 01/01/2023 - "Effects of probenecid and brilliant blue G on rat enteric glial cells following intestinal ischemia and reperfusion." 01/01/2022 - "Research has shown that Brilliant Blue G (BBG), a P2X7 receptor antagonist, restores enteric neurons following ischemia and reperfusion. " 01/01/2019 - "Our work analyzed the effects of a P2X7 receptor antagonist, Brilliant Blue G (BBG), on rat ileum myenteric plexus following ischemia and reperfusion (ISR) induced by 45 min of ileal artery occlusion with an atraumatic vascular clamp with 24 h (ISR 24-h group) or 14 d of reperfusion (ISR 14-d group). " 01/01/2019 - "Here, we investigated the differential proteomic profiles of mouse brain homogenate with 3 h of middle cerebral artery occlusion (MCAO) ischemia, or sham, using Coomassie Brilliant Blue staining, followed by mass spectrometry. " 01/01/2023 - "This study examined the effects of probenecid (PB) and brilliant blue G (BBG), which are antagonists of the pannexin-1 channel and P2X7 receptor, respectively, on rat ileum enteric glial cells after on ischemia and reperfusion. "
5.	Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage) 12/01/2013 - "Brilliant blue G significantly improved neurobehavioral function and ameliorated brain water content at 24 and 72 hours after subarachnoid hemorrhage. " 12/01/2013 - "The animals were intraperitoneally treated with brilliant blue G (30 mg/kg) at 30 minutes after subarachnoid hemorrhage. " 12/01/2013 - "This study examined whether brilliant blue G treatment ameliorates early brain injury after experimental subarachnoid hemorrhage, specifically via inhibiting p38 mitogen-activated protein kinase-related proapoptotic pathways. " 12/01/2013 - "Experiment 1 implemented sham-operated rats (sham) and subarachnoid hemorrhage animals, which received vehicle (subarachnoid hemorrhage + vehicle), brilliant blue G (subarachnoid hemorrhage + brilliant blue G), or brilliant blue G plus 2'(3')-O-(4-Benzoylbenzoyl)adenosine 5'-triphosphate (BzATP) (subarachnoid hemorrhage + brilliant blue G + BzATP). " 12/01/2013 - "Inhibition of P2X7 receptor by brilliant blue G or P2X7 receptor small interfering RNA can prevent early brain injury via p38 mitogen-activated protein kinase after subarachnoid hemorrhage."

Related Drugs and Biologics

1.	Coloring Agents (Dyes)
2.	Purinergic P2X7 Receptors
3.	polyacrylamide
4.	p38 Mitogen-Activated Protein Kinases
5.	Hydrogels
6.	3- (5- (2,3- dichlorophenyl)- 1H- tetrazol- 1- yl)methylpyridine
7.	triphenylmethane
8.	Retinaldehyde (Retinal)
9.	Trypan Blue
10.	Inflammasomes

Related Therapies and Procedures

1.	Vitrectomy
2.	Phacoemulsification
3.	Photothermal Therapy
4.	Lasers (Laser)
5.	Intraperitoneal Injections