|1.||Reimschuessel, Renate: 8 articles (06/2014 - 09/2008)|
|2.||Gamboa da Costa, Gonçalo: 4 articles (01/2013 - 02/2011)|
|3.||Evans, Eric R: 3 articles (06/2014 - 08/2011)|
|4.||Stine, Cynthia B: 3 articles (06/2014 - 08/2011)|
|5.||Chen, Yng-Tay: 3 articles (03/2014 - 12/2009)|
|6.||Liao, Jiunn-Wang: 3 articles (03/2014 - 12/2009)|
|7.||Tsai, Fuu-Jen: 3 articles (03/2014 - 01/2010)|
|8.||Hasbrouck, Nicholas R: 3 articles (10/2012 - 08/2011)|
|9.||Gieseker, Charles M: 3 articles (10/2012 - 09/2008)|
|10.||Beland, Frederick A: 3 articles (07/2012 - 02/2011)|
|1.||Renal Insufficiency (Renal Failure)
01/01/2014 - "However, after melamine and cyanuric acid administration cessation, crystal deposition and renal failure improved and did not cause growth arrest. "
01/01/2008 - "While there are very few data on the nephrotoxic effects of melamine in humans, studies on animals have shown that melamine, in particular in combination with cyanuric acid, causes deposition and precipitation of birefringent crystals thereby causing renal failure. "
10/01/2014 - "In 2007, renal failure and death in pets were linked to pet food containing both melamine (MEL) and cyanuric acid (CYA). "
01/01/2014 - "Younger rats experienced more severe renal failure and greater renal crystal deposition following melamine and cyanuric acid administration. "
01/01/2013 - "In 2007 and 2008, renal stone formation and kidney damage in human infants were linked to consumption of melamine (MEL)-contaminated infant formula, as well as renal failure and death in pets due to pet food containing both MEL and cyanuric acid (CYA). "
|2.||Body Weight (Weight, Body)
12/01/2013 - "The USFDA subsequently designed studies to determine residue levels in muscle, serum, and kidneys of catfish and trout given a single gavage dose of 20 mg/kg body weight (BW) of melamine, cyanuric acid, or 20 mg/kg BW of both compounds simultaneously. "
10/01/2012 - "We report here a LC-MS/MS method to quantify and confirm melamine and cyanuric acid in serum from channel catfish and rainbow trout with a limit of quantification of 0.8 μg/mL. The method was applied to serum samples from a residue depletion study in which fish were given a single oral dose of 20 mg/kg body weight melamine, cyanuric acid, or both compounds together. "
02/01/2011 - "The observed adverse effect level (8.6 mg/kg bw [body weight]/day) and benchmark dose modeling data (8.4-10.9 mg/kg bw/day) determined in this study suggest that the tolerable daily intake values derived from studies conducted with melamine alone may underestimate the risk from coexposures to melamine and cyanuric acid."
04/01/2010 - "We report the results of a good laboratory practices (GLP) study to determine melamine and cyanuric acid residues in catfish and trout filets harvested at 1, 3, 7, 14, 28, and 42 days after a single oral dose of 20 mg/kg body weight of melamine, cyanuric acid, or melamine and cyanuric acid together. "
01/01/2014 - "Body weights were measured weekly; on days 0, 28, 90, and 180 after the 28-day period of melamine and cyanuric acid administration, serum samples and kidney sections were obtained. "
|3.||Acute Kidney Injury (Acute Renal Failure)
11/26/2010 - "Pathological studies indicated that the melamine-induced acute renal failure was related to the concurrence of melamine and other triazine analogs such as cyanuric acid. "
10/01/2013 - "Melamine and cyanuric acid (M/CA), when orally administered together to rats, can induce crystal formation within renal tubules and cause acute kidney injury. "
04/01/2010 - "In rats administered the high-dose melamine/cyanuric acid [120 mg/kg/day], crystals were found in the proximal tubular lumens of the renal cortex on day 3, but acute renal failure resulted in death by day 7. Polarized light optical microphotography and scanning electron microscopy revealed tubular lumens occluded by a layer of axle-shaped crystals. "
11/01/2007 - "The results demonstrate that the combination of melamine and cyanuric acid is responsible for acute renal failure in cats."
03/01/2012 - "In China, the effect of melamine or melamine-cyanuric acid adulteration lead to kidney stone development and acute renal failure in thousands of Chinese infants. "
|4.||Urinary Calculi (Urinary Calculus)
01/01/2010 - "In this study, we made an artificial stone composition and examine under IR absorbance by mixing equal molar ratios of melamine/cyanuric acid with different types of human urinary stones, and established a reference of IR analysis for the identification of melamine/cyanuric acid-containing human urinary tract stones. "
09/01/2011 - "The main constituent of the urinary calculus was melamine (> 90%), with a little uric acid and traces of cyanuric acid. "
08/01/2011 - "Urinary stones contained melamine and uric acid, but no cyanuric acid. "
03/01/2010 - "Melamine ingestion has been implicated in stone formation when co-ingested with cyanuric acid, but will cause urinary stones in infants when large amounts of melamine alone are ingested."
10/01/2010 - "Melamine has been the main factor leading to infant urinary calculi occurring on a rather wide scale in China in 2008, which were the results of a rapid aggradation of metabolites such as cyanuric acid diamide, cyanuric acid, etc., causing uric acid stone to accumulate. "
01/01/2010 - "Identification of melamine/cyanuric acid-containing nephrolithiasis by infrared spectroscopy."
01/01/2015 - "The objective of this study is to examine the effects of apocynin on melamine-cyanuric acid mixture (MCM)-induced nephrolithiasis in vitro and in vivo. "
11/11/2010 - "Co-contamination, but not mammalian cell conversion of melamine to cyanuric acid the likely cause of melamine-cyanurate nephrolithiasis."
|3.||Uric Acid (Urate)