cyanuric acid

RN given refers to parent cpd

Also Known As:

cyanuric acid, cupric ammonia (+2) salt; cyanuric acid, disodium salt; cyanuric acid, monopotassium salt; cyanuric acid, monosodium salt; cyanuric acid, potassium salt; cyanuric acid, sodium salt; cyanuric acid, trisodium salt; s-triazine-2,4,6-triol; 1,3,5-triazine-2,4,6(1H,3H,5H)-trione

Networked: 66 relevant articles (2 outcomes, 11 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Triazines: 306
    - cyanuric acid: 66

Experts

1.	Reimschuessel, Renate: 8 articles (06/2014 - 09/2008)
2.	Gamboa da Costa, Gonçalo: 5 articles (01/2013 - 02/2011)
3.	Evans, Eric R: 3 articles (06/2014 - 08/2011)
4.	Stine, Cynthia B: 3 articles (06/2014 - 08/2011)
5.	Chen, Yng-Tay: 3 articles (03/2014 - 12/2009)
6.	Liao, Jiunn-Wang: 3 articles (03/2014 - 12/2009)
7.	Tsai, Fuu-Jen: 3 articles (03/2014 - 01/2010)
8.	Gieseker, Charles M: 3 articles (10/2012 - 09/2008)
9.	Hasbrouck, Nicholas R: 3 articles (10/2012 - 08/2011)
10.	Beland, Frederick A: 3 articles (07/2012 - 02/2011)

Related Diseases

1.	Renal Insufficiency (Renal Failure) 02/08/2014 - "However, after melamine and cyanuric acid administration cessation, crystal deposition and renal failure improved and did not cause growth arrest. " 10/09/2008 - "While there are very few data on the nephrotoxic effects of melamine in humans, studies on animals have shown that melamine, in particular in combination with cyanuric acid, causes deposition and precipitation of birefringent crystals thereby causing renal failure. " 10/01/2014 - "In 2007, renal failure and death in pets were linked to pet food containing both melamine (MEL) and cyanuric acid (CYA). " 02/08/2014 - "Younger rats experienced more severe renal failure and greater renal crystal deposition following melamine and cyanuric acid administration. " 06/01/2013 - "The mice from co-administration groups of melamine and cyanuric acid were not eating, and were most likely in renal failure. "
2.	Kidney Calculi (Kidney Stone) 03/20/2014 - "Kidney stone distribution caused by melamine and cyanuric acid in rats." 02/13/2013 - "We report that cyanuric acid can be produced in the gut by microbial transformation of melamine and serves as an integral component of the kidney stones responsible for melamine-induced renal toxicity in rats. " 08/01/2010 - "In the fall of 2007 pet food contaminated with melamine and cyanuric acid caused kidney stones in thousands of animals. " 03/01/2013 - "Cases of pet poisoning and infant renal calculus have attracted much attention to the toxicity of melamine and its derivatives, such as cyanuric acid. " 03/01/2012 - "In China, the effect of melamine or melamine-cyanuric acid adulteration lead to kidney stone development and acute renal failure in thousands of Chinese infants. "
3.	Body Weight (Weight, Body) 01/01/2019 - "The median estimated daily dietary intakes (including concentrations reported for dairy products in our previous study) of melamine and cyanuric acid were in the ranges of 13.4-72.7 and 75.4-347 ng/kg body weight/day, respectively, for various age groups. " 12/01/2013 - "The USFDA subsequently designed studies to determine residue levels in muscle, serum, and kidneys of catfish and trout given a single gavage dose of 20 mg/kg body weight (BW) of melamine, cyanuric acid, or 20 mg/kg BW of both compounds simultaneously. " 10/01/2012 - "We report here a LC-MS/MS method to quantify and confirm melamine and cyanuric acid in serum from channel catfish and rainbow trout with a limit of quantification of 0.8 μg/mL. The method was applied to serum samples from a residue depletion study in which fish were given a single oral dose of 20 mg/kg body weight melamine, cyanuric acid, or both compounds together. " 02/01/2011 - "The observed adverse effect level (8.6 mg/kg bw [body weight]/day) and benchmark dose modeling data (8.4-10.9 mg/kg bw/day) determined in this study suggest that the tolerable daily intake values derived from studies conducted with melamine alone may underestimate the risk from coexposures to melamine and cyanuric acid." 04/01/2010 - "We report the results of a good laboratory practices (GLP) study to determine melamine and cyanuric acid residues in catfish and trout filets harvested at 1, 3, 7, 14, 28, and 42 days after a single oral dose of 20 mg/kg body weight of melamine, cyanuric acid, or melamine and cyanuric acid together. "
4.	Acute Kidney Injury (Acute Renal Failure) 01/01/2019 - "To determine whether US children have measurable concentrations of these chemicals in their bodies and whether they are at greater risk of acute kidney injury, we measured melamine and cyanuric acid exposure in a cohort of US children and determined their relationship with markers of kidney injury. " 10/01/2013 - "Melamine and cyanuric acid (M/CA), when orally administered together to rats, can induce crystal formation within renal tubules and cause acute kidney injury. " 04/01/2010 - "In rats administered the high-dose melamine/cyanuric acid [120 mg/kg/day], crystals were found in the proximal tubular lumens of the renal cortex on day 3, but acute renal failure resulted in death by day 7. Polarized light optical microphotography and scanning electron microscopy revealed tubular lumens occluded by a layer of axle-shaped crystals. " 11/01/2007 - "The results demonstrate that the combination of melamine and cyanuric acid is responsible for acute renal failure in cats." 01/01/2019 - "Melamine and cyanuric acid, which are currently used in a variety of common consumer products and present in foods, have been implicated in the development of urolithiasis and acute kidney injury in Chinese children. "
5.	Urinary Calculi (Urinary Calculus) 01/01/2010 - "In this study, we made an artificial stone composition and examine under IR absorbance by mixing equal molar ratios of melamine/cyanuric acid with different types of human urinary stones, and established a reference of IR analysis for the identification of melamine/cyanuric acid-containing human urinary tract stones. " 03/01/2010 - "Melamine ingestion has been implicated in stone formation when co-ingested with cyanuric acid, but will cause urinary stones in infants when large amounts of melamine alone are ingested." 09/01/2011 - "The main constituent of the urinary calculus was melamine (> 90%), with a little uric acid and traces of cyanuric acid. " 08/01/2011 - "Urinary stones contained melamine and uric acid, but no cyanuric acid. " 10/01/2010 - "Melamine has been the main factor leading to infant urinary calculi occurring on a rather wide scale in China in 2008, which were the results of a rapid aggradation of metabolites such as cyanuric acid diamide, cyanuric acid, etc., causing uric acid stone to accumulate. "

Related Drugs and Biologics

1.	melamine
2.	Catechin (Z 7300)
3.	Triazines
4.	acetovanillone (apocynin)
5.	Uric Acid (Urate)
6.	melamine cyanurate
7.	Proteins (Proteins, Gene)
8.	Nitrogen
9.	Creatinine
10.	Inflammasomes

Related Therapies and Procedures

1.	Oral Administration
2.	Bioreactors (Bioreactor)
3.	Resuscitation
4.	Electrodes (Electrode)