|1.||Xu, Yong: 1 article (08/2014)|
|2.||Zhou, Feng: 1 article (08/2014)|
|3.||Fang, Jian-Feng: 1 article (08/2014)|
|4.||Zhu, Yun-Rong: 1 article (08/2014)|
|5.||Zhang, Yun-Qing: 1 article (08/2014)|
|6.||Deng, Xiong-Wei: 1 article (08/2014)|
|7.||Dufrasne, François: 1 article (06/2013)|
|8.||Urban, Ernst: 1 article (06/2013)|
|9.||Moreno Y Banuls, Laetitia: 1 article (06/2013)|
|10.||Zehl, Martin: 1 article (06/2013)|
01/01/2012 - "Our results demonstrated that bufotalin is a powerful sensitizer of death receptor-induced apoptosis in cancer cells."
10/05/2012 - "These results indicate that bufotalin has a promising potential to become a novel anti-cancer agent for the treatment of liver cancer with multidrug resistance."
06/28/2013 - "Thus, the current study revealed that various bufadienolides, including gamabufotalin rhamnoside (1a), bufotalin (2a), and hellebrin (3a), displayed higher growth inhibitory activities for various human cancer cell lines when compared to ouabain and digoxin. "
|2.||Hepatocellular Carcinoma (Hepatoma)
|3.||Breast Neoplasms (Breast Cancer)
01/01/2012 - "Bufalin, bufotalin and gamabufotalin, key bufadienolides, significantly sensitize human breast cancer cells with differing ER-alpha status to apoptosis induction by the TNF-related apoptosis-inducing ligand (TRAIL). "
04/01/2011 - "In the current study, we found that bufalin, bufotalin and gamabufotalin, key members of bufadienolides isolated from a traditional Chinese medicine ChanSu, significantly potentiated human breast cancer cells with different status of ER-alpha to apoptosis induction of TRAIL, as evidenced by enhanced Annexin V/FITC positive cells (apoptotic cells), cytoplasmic histone-associated-DNA-fragments, membrane permeability transition (MPT), caspases activation and PARP cleavage. "
08/15/2014 - "In this study, we examined the potential anti-osteoblastoma function of bufotalin, and studied the underlying mechanisms. "
08/15/2014 - "Bufotalin might be investigated as a novel anti-osteoblastoma agent. "
08/15/2014 - "In summary, our results suggest that ER stress contributes to bufotalin-induced apoptosis in osteoblastoma cells. "
08/15/2014 - "Our results showed that bufotalin induced osteoblastoma cell death and apoptosis in dose- and time-dependent manners. "
08/15/2014 - "Bufotalin-induced apoptosis in osteoblastoma cells is associated with endoplasmic reticulum stress activation."
|5.||Body Weight (Weight, Body)
|6.||Ouabain (G Strophanthin)
|8.||DNA (Deoxyribonucleic Acid)
|1.||Chinese Traditional Medicine (Traditional Chinese Medicine)
|2.||Heterologous Transplantation (Xenotransplantation)