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tiadenol
structure
Also Known As:
2,2'-(decamethylenedithio)-diethanol; BS 530; Fonlipol; LL 1558; bis(2- hydroxyethylthio)-1,10-decane; bis(hydroxy-2-ethylthio)-1,10-decane; thiadenol; tiadenolo; 2,2'-(1,10-decanediylbis(thio))bis-ethanol
Networked:
19
relevant articles (
1
outcomes,
1
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Organic Chemicals: 133
Alcohols: 595
Fatty Alcohols: 172
tiadenol: 19
Lipids: 114793
Fatty Alcohols: 172
tiadenol: 19
Related Diseases
1.
Hypertriglyceridemia
11/01/1981 - "
Tiadenol administration was remarkably effective in inhibiting fructose induced hypertriglyceridemia in diet responsive type IV patients; it was ineffective in patients with stable, diet refractory, hypertriglyceridemia.
"
04/01/1985 - "
Effects of tiadenol and clofibrate on plasma post heparin lipolytic hepatic, extrahepatic and monoglyceride hydrolase activities in rats with hypertriglyceridemia induced by a sucrose rich diet.
"
2.
Hypertrophy
07/01/1976 - "
[The action of tiadenol on compensatory hypertrophy of the liver in the rat].
"
06/15/1980 - "
By hystological and electronmicroscopical study liver of rats treated with tiadenol at a daily dose of 100 and 200 mg for 30 days, we could demonstrate: lack of necrosis and interstitial phlogosis and, especially in those animals treated with greater doses, numerical increase of peroxisomes, hypertrophy of SER and RER and a lesser regularity of glycogen distribution.
"
3.
Necrosis
06/15/1980 - "
By hystological and electronmicroscopical study liver of rats treated with tiadenol at a daily dose of 100 and 200 mg for 30 days, we could demonstrate: lack of necrosis and interstitial phlogosis and, especially in those animals treated with greater doses, numerical increase of peroxisomes, hypertrophy of SER and RER and a lesser regularity of glycogen distribution.
"
4.
Hyperlipidemias (Hyperlipidemia)
01/01/1981 - "
[Tiadenol in the treatment of primary hyperlipidemias].
"
07/01/1976 - "
[The effect of tiadenol on type IIA hyperlipidemias].
"
10/31/1979 - "
[Tolerability and side-effects of bis-(hydroxy-2-ethylthio)-1,10-decane (BS 530) as compared with clofibrate in the therapy of hyperlipemia].
"
06/01/1987 - "
Likewise, it is equally effective as tiadenol in preventing Triton-induced hyperlipidemia and Nath diet induced hypercholesterolemia; in addition tiadenol-disulfoxide is slightly more effective than tiadenol in increasing HDL-cholesterol in hypercholesterolemic rats.
"
01/01/1984 - "
Bendaline, like tiadenol, clofibrate and clofibric acid generally inhibits: a) some hyperlipemias and lipoidoses induced by either an increased exogenous supply of lipids or the stimulation of cholesterol synthesis or mobilization of lipids; b) platelet aggregation in vitro.
"
5.
Hyperlipoproteinemias
09/01/1980 - "
[Tiadenol treatment of hyperlipoproteinemia in maturity onset diabetes].
"
11/01/1983 - "
Clofibrate and tiadenol treatment in hyperlipoproteinemias.
"
01/01/1973 - "
[Effects on the serum lipids of bis (hydroxy-2 ethylthio) 1,10 decane (LL 1558) and clofibrate, based on 91 cases of primary hyperlipoproteinemia].
"
Related Drugs and Biologics
1.
Fructose
2.
Glycogen
3.
Clofibrate
4.
Lipids
5.
Tablets
6.
Sucrose (Saccharose)
7.
Monoacylglycerol Lipases
8.
HDL Cholesterol
9.
Mixed Function Oxygenases (Monooxygenases)
10.
Heparin (Liquaemin)
Related Therapies and Procedures
1.
Therapeutics