panaxadiol

a protopanaxadiol with the side chain cyclized into a pyran which is an artifact of acidic hydrolysis; RN refers to (3 beta,12 beta,20R)-isomer

Also Known As:

panaxadiol, (3beta,12beta)-isomer; (3 beta,12 beta,20R)-20,25-epoxydammarane-3,12- diol

Networked: 34 relevant articles (4 outcomes, 10 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Triterpenes: 2493
      - Ginsenosides: 1010
        panaxadiol: 34
Carbohydrates: 22023
- Glycosides: 2119
  - Saponins: 2867
    - Ginsenosides: 1010
      - panaxadiol: 34

Experts

1.	Zhao, Yuqing: 4 articles (11/2021 - 01/2017)
2.	Wang, Chong-Zhi: 4 articles (02/2013 - 11/2009)
3.	Yuan, Chun-Su: 4 articles (02/2013 - 11/2009)
4.	Gao, Rui-Lan: 3 articles (01/2022 - 03/2018)
5.	Xiao, Shengnan: 3 articles (11/2021 - 01/2017)
6.	Du, Guang-Jian: 3 articles (02/2013 - 01/2010)
7.	Jin, Hong Lan: 2 articles (01/2022 - 01/2020)
8.	Jin, Xuejun: 2 articles (01/2022 - 01/2020)
9.	Li, Ming Yue: 2 articles (01/2022 - 01/2020)
10.	Ma, Juan: 2 articles (01/2022 - 01/2020)

Related Diseases

1.	Aplastic Anemia (Anemia, Hypoplastic) 12/01/2019 - "To investigate the potential efficacy of panaxadiol saponins component (PDS-C) in the treatment of aplastic anemia (AA) model mice. " 05/01/2023 - "Panaxadiol saponin (PND) is a latent targeted drug for the treatment of aplastic anemia (AA). " 05/01/2023 - "Panaxadiol saponin ameliorates ferroptosis in iron-overload aplastic anemia mice and Meg-01 cells by activating Nrf2/HO-1 and PI3K/AKT/mTOR signaling pathway." 02/01/2016 - "To evaluate the efficacy and safety of Pai-Neng-Da Capsule (panaxadiol saponins component, PND), a new Chinese patent medicine, on patients with chronic aplastic anemia (CAA) and to explore the optimal therapeutic regimen for CAA. " 01/01/2022 - "To evaluate the efficacy and safety of Pai-Neng-Da Capsule (, panaxadiol saponins component, PNDC) in combination with the cyclosporine and androgen for patients with chronic aplastic anemia (CAA). "
2.	Iron Overload 05/01/2023 - "Panaxadiol saponin ameliorates ferroptosis in iron-overload aplastic anemia mice and Meg-01 cells by activating Nrf2/HO-1 and PI3K/AKT/mTOR signaling pathway."
3.	Pancytopenia 03/01/2018 - "To investigate the potential efficacy of panaxadiol saponins component (PDS-C), a biologically active fraction isolated from total ginsenosides, to reverse chemotherapy-induced myelosuppression and pancytopenia caused by cyclophamide (CTX). "
4.	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 06/01/2023 - "Ginseng-derived panaxadiol ameliorates STZ-induced type 1 diabetes through inhibiting RORγ/IL-17A axis."
5.	Cytopenia 03/01/2018 - "Ginseng-Derived Panaxadiol Saponins Promote Hematopoiesis Recovery in Cyclophosphamide-Induced Myelosuppressive Mice: Potential Novel Treatment of Chemotherapy-Induced Cytopenias."

Related Drugs and Biologics

1.	Saponins
2.	Ginsenosides
3.	Cyclophosphamide (Cytoxan)
4.	Proteins (Proteins, Gene)
5.	Dammaranes
6.	panaxatriol
7.	Inflammasomes
8.	Caspase 8 (Caspase-8)
9.	Lipopolysaccharides
10.	Ligands

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)