azobis(isobutyronitrile) (AIBN)

blowing agent for elastomers & plastics; initiator for free radical reactions; structure

Also Known As:

AIBN; azobisisobutyronitrile; 2,2'-azobisisobutyronitrile; 2,2'-azobis(2-methylpropionitrile)

Networked: 6 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Nitriles: 227
  - azobis(isobutyronitrile): 6

Experts

1.	Shin, Su-Mi: 1 article (01/2021)
2.	Sung, A-Young: 1 article (01/2021)
3.	Chea, JongMyoung: 1 article (10/2015)
4.	Clive, Derrick L J: 1 article (10/2015)
5.	Iida, Takashi: 1 article (10/2013)
6.	Kawamoto, Hiroaki: 1 article (10/2013)
7.	Maekawa, Masamitsu: 1 article (10/2013)
8.	Mano, Nariyasu: 1 article (10/2013)
9.	Ohmori, Yuusuke: 1 article (10/2013)
10.	Shimada, Miki: 1 article (10/2013)

Related Diseases

1.	Dehydration (Water Stress) 10/16/2015 - "Reaction with vinyllithium, 6-exo-trig radical cyclization (Bu3SnH, AIBN, PhMe, 110 °C), dehydration (P2O5, H3PO4), and demethylation (BBr3) gave (+)-ipalbidine with ee >99%. " 10/01/2013 - "The principal reactions involved were (1) cis-4α,5α-dihydroxylation of the allylic 3β-acetoxy-Δ(4) intermediate with in situ generated RuO4 and subsequent dehydration with SOCl2, (2) direct 4β-hydroxylation of cholesterol with selenium dioxide, and (3) regioselective dehydrogenation at C-7/-8 of the resulting 4α- and 4β-hydroxylated derivatives with 1,3-dibromo-5,5-dimethylhydantoin/azobisisobutyronitrile, followed by tetrabutyl ammonium bromide/tetrabutyl ammonium fluoride. " 04/17/1998 - "As a model study, conjugate addition of 4-(trimethylsilyl)-3-butynylmagnesium chloride to enone 7 followed by trapping of the enolate with chlorotrimethylsilane gave trimethysilyl enol ether 8. Iodination of 8 with a mixture of NaI and m-CPBA afforded iodo ketone 6. Radical cyclization of 6 effected by Bu(3)SnH and AIBN gave 5. Epoxidation of 5 with m-CPBA yielded epoxy ketone 9. Desilylation and rearrangement of 9 by formic acid gave aldehyde 4. Aldol condensation and dehydration furnished angular triquinane skeleton 3. Total synthesis of (-)-5-oxosilphiperfol-6-ene (1) was accomplished in 12 steps starting from keto ester 14 based on this route. "
2.	Sudden Infant Death (SID) 01/01/2021 - "This study prepared silicone hydrogel ophthalmic lenses using 2-hydroxyethylmethacrylate (HEMA), synthesized silicone monomer (SID), dimethylarsinic acid (DMA), N-hydroxyethyl acrylamide (HEA), ethylene glycol dimethacrylate (a crosslinking agent, EGDMA), and azobisisobutyronitrile (an initiator, AIBN). "
3.	Rupture 10/30/2003 - "The reactivity of the fluorinated radical generated by rupture of the C-I bond has been preliminarily assessed by reductive deiodination with tributyltin hydride/AIBN and intermolecular allylation using the Keck reaction."
4.	Prostatic Neoplasms (Prostate Cancer) 01/01/2007 - "To develop new radiopharmaceuticals for interventional radionuclide therapy of locally recurrent prostate cancer, poly[N-(3-aminopropyl)methacrylamide] [poly(APMA)] polymers were synthesized by free radical precipitation polymerization in acetone-dimethylsulfoxide using N,N'-azobis(isobutyronitrile) as the initiator. "

Related Drugs and Biologics

1.	azobis(isobutyronitrile) (AIBN)
2.	Hydrogels
3.	Silicones
4.	Ketones
5.	Ether (Diethyl Ether)
6.	Esters
7.	Chlorides
8.	Cacodylic Acid (Cacodylate)
9.	Aldehydes
10.	3-hydroxybutanal (aldol)

Related Therapies and Procedures

1.	Lenses
2.	Therapeutics