bisabolol (levomenol)

monocyclic sesquiterpene alcohol with strong bacteriocidal effects, especilly against M. Tuberc.; isolated from seed plant Populus tacamacaha; RN given refers to cpd without isomeric desigation

Also Known As:

Networked: 95 relevant articles (12 outcomes, 24 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Suzuki, Hisanori: 6 articles (01/2012 - 03/2004)
2.	Azimullah, Sheikh: 4 articles (10/2020 - 10/2018)
3.	Ojha, Shreesh: 4 articles (10/2020 - 10/2018)
4.	Rigo, Antonella: 4 articles (05/2018 - 04/2011)
5.	Vinante, Fabrizio: 4 articles (05/2018 - 04/2011)
6.	Cavalieri, Elisabetta: 4 articles (01/2012 - 03/2004)
7.	Laham, Farah: 3 articles (01/2020 - 10/2018)
8.	Kokuryo, Toshio: 3 articles (01/2017 - 12/2011)
9.	Nagino, Masato: 3 articles (01/2017 - 12/2011)
10.	Yokoyama, Yukihiro: 3 articles (01/2017 - 12/2011)

Related Diseases

1.	Pancreatic Neoplasms (Pancreatic Cancer) 02/01/2016 - "Further investigations are necessary to clarify the precise mechanisms of α-bisabolol activity for clinical application as a novel treatment for pancreatic cancer. " 01/01/2017 - "The aim of this study was to develop α-bisabolol derivatives which are more potent than the parent compound and may be clinically useful against pancreatic cancer. " 02/01/2016 - "In this study, demonstrated that α-bisabolol suppressed the invasiveness and motility of a pancreatic cancer cell line. " 08/15/2008 - "The present study extends these data demonstrating the apoptosis-inducing action of alpha-bisabolol towards highly malignant human pancreatic carcinoma cell lines without affecting human fibroblast viability. " 03/01/2023 - "α-Bisabolol suppresses phosphorylation of FAK 397 and impairs cytoskeletal polymerization in a pancreatic cancer cell line. "
2.	Inflammation (Inflammations) 12/01/2011 - "In this study, (-)-α-bisabolol was tested in standardised rodent models by gavage administration at doses of 100 and 200 mg/kg in the models of inflammation and 25 and 50 mg/kg in the models of nociception. " 09/10/2022 - "Based on the results observed, it can be concluded that α-Bisabolol has potential to attenuate DOX-induced nephrotoxicity by inhibiting oxidative stress and inflammation mediated activation of NF-κB/MAPK signaling alongwith intrinsic pathway of apoptosis in rats. " 01/01/2014 - "These findings suggested that α-(-)-bisabolol may be a useful therapeutic candidate for the treatment of skin inflammation. " 03/01/2011 - "(-)-α-Bisabolol attenuates visceral nociception and inflammation in mice." 04/01/1969 - "[On the inflammation inhibitory effect of (-)-alpha-bisabolol, an essential component of chamomilla oil]."
3.	Visceral Leishmaniasis (Kala Azar) 06/26/2015 - "The aim of the present study was to assess the in vitro and in vivo activity of (-)-α-bisabolol (1) against the etiological agents of visceral leishmaniasis. " 06/26/2015 - "(-)-α-Bisabolol (1) is a nontoxic compound that was proven to be active against visceral leishmaniasis in an in vivo murine model orally. " 06/26/2015 - "(-)-α-Bisabolol, a Promising Oral Compound for the Treatment of Visceral Leishmaniasis." 10/01/2016 - "The sesquiterpene (-)-α-bisabolol is effective in vivo against visceral leishmaniasis due to Leishmania infantum, but its mechanism of action remains elusive. "
4.	Leg Ulcer 09/01/2015 - "The efficacy of an innovative spray formulation of ozonated oil and α-bisabolol combination in the topical treatment of chronic venous leg ulcers was evaluated compared with standard epithelialization cream. " 09/01/2015 - "Randomized, controlled study of innovative spray formulation containing ozonated oil and α-bisabolol in the topical treatment of chronic venous leg ulcers."
5.	Eczema 06/01/2016 - "The study moisturizer containing the occlusive ingredients of dimethicone and shea butter oil; the humectant ingredients of glycerin, vitamin B, sodium PCA, and sodium hyaluronate; the barrier repair ingredients of ceramide 3, cholesterol, phytosphingosine, ceramide 6 II, and ceramide 1; and the botanical anti-inflammatories allantoin and bisabolol were helpful in reducing the signs and symptoms of mild-to-moderate eczema."

Related Drugs and Biologics

1.	Sesquiterpenes
2.	Anti-Inflammatory Agents (Anti-Inflammatories)
3.	Isoproterenol (Isoprenaline)
4.	Hygroscopic Agents
5.	Vitamin B Complex (B Vitamins)
6.	Sodium
7.	Hyaluronic Acid (Hyaluronan)
8.	Glycerol (Glycerine)
9.	Cholesterol
10.	Ceramides

Related Therapies and Procedures

1.	Topical Administration
2.	Radiotherapy
3.	Therapeutics
4.	Photochemotherapy (Photodynamic Therapy)
5.	Subcutaneous Injections