trofosfamide

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53 relevant articles (9 outcomes, 8 trials/studies) found for this Bio-Agent

Description: cyclophosphamide analog; structure

Also Known As:

Baxter Oncology brand of trofosfamide; Genoxal Trofosfamida; Ixoten; N,N,N'-tris(2-chloroethyl)-N'-O-propylene phosphoric acid ester diamide; Prasfarma brand of trofosfamide; Z 4828; trophosphamide; N,N-3'-tris(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine, 2-oxide

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 40

Hydrocarbons: 382

Halogenated Hydrocarbons: 28

Mustard Compounds: 3

Nitrogen Mustard Compounds: 1

Phosphoramide Mustards: 3

Cyclophosphamide: 14959

trofosfamide: 53

Organophosphorus Compounds: 126

Phosphoramide Mustards: 3

Cyclophosphamide: 14959

trofosfamide: 53

Experts

1.	Reichle, Albrecht: 3 articles (12/2004 - 11/2003)
2.	Vogt, Thomas: 3 articles (12/2004 - 11/2003)
3.	Wagner, T: 2 articles (10/2006 - 12/2005)
4.	Hafner, Christian: 2 articles (12/2004 - 11/2003)
5.	Landthaler, Michael: 2 articles (12/2004 - 11/2003)
6.	Bross, Klaus: 2 articles (11/2004 - 11/2003)
7.	Andreesen, Reinhard: 2 articles (11/2004 - 11/2003)
8.	Berand, Anna: 2 articles (11/2004 - 11/2003)
9.	Bataille, Frauke: 2 articles (11/2004 - 11/2003)
10.	Kanz, L: 2 articles (07/2004 - 03/2003)

Related Diseases

1.	Neoplasms (Cancer) 03/01/2003 - "Trofosfamide, an alkylating agent, has been shown to be effective in several solid and haematological tumors" 04/01/2007 - "Due to tumor progression after 2 cycles, she was switched to oral trofosfamide (150 mg daily)" 12/01/2004 - "However, the optimal dose of trofosfamide for patients with advanced cancer has not been systematically investigated yet" 07/01/2004 - "We report herein a case of a 83-year-old female patient with a disseminated malignant peripheral nerve sheath tumor treated with trofosfamide developing pulmonal toxicity" 06/01/1997 - "Trofosfamide: a review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in the oral treatment of cancer." Get all the results and reference details, order at left...
2.	Non-Hodgkin Lymphoma (Lymphosarcoma) 01/01/1994 - "Complete remission after repeated trofosfamide treatment in relapsing high-grade malignant non-Hodgkin's lymphoma--a case report." 12/01/1995 - "Trofosfamide is effective in refractory non-Hodgkin's lymphoma." 01/01/1991 - "Twenty-three patients (12 females, 11 males) with malignant non-Hodgkin's lymphoma were treated with oral trofosfamide 50 mg t.i.d" 01/01/1991 - "Trofosfamide in non-Hodgkin's lymphoma" 12/01/2002 - "A few studies have shown that trofosfamide, an oral alkylating agent, may be effective as palliative treatment in non-Hodgkin's lymphoma" Get all the results and reference details, order at left...
3.	Sarcoma (Soft Tissue Sarcoma) 03/01/2003 - "CONCLUSION: No objective remission was observed with oral low-dose trofosfamide in heavily pretreated soft tissue sarcoma patients, but almost half of the patients achieved disease stabilisation for half a year" 03/01/2003 - "Phase II trial of trofosfamide in patients with advanced pretreated soft tissue sarcomas." 12/01/2002 - "Oral trofosfamide: an active and well-tolerated maintenance therapy for adult patients with advanced bone and soft tissue sarcomas" 01/01/1995 - "Oral trofosfamide: an active drug in the treatment of soft-tissue sarcoma." 03/01/2003 - "The moderate toxicity profile observed in this study allows the consideration of trofosfamide as a reasonable palliative treatment option for patients with soft tissue sarcoma." Get all the results and reference details, order at left...
4.	Lymphoma (Lymphomas) 09/01/2004 - "Treatment of primary intraocular lymphoma with oral trofosfamide: report of two cases and review of the literature." 03/01/1997 - "Trofosfamide as a salvage treatment with low toxicity in malignant lymphoma" 01/01/1979 - "Ixoten therapy in malignant lymphomas]" 03/01/1997 - "Trofosfamide is an interesting and a non-toxic palliative treatment for relapsing malignant lymphomas especially in elderly patients." 03/01/1997 - "37 patients with disease progression after prior treatment for malignant lymphoma (27 low grade, 7 high grade and 3 Hodgkin's) were treated with oral trofosfamide daily" Get all the results and reference details, order at left...
5.	Hemangiosarcoma (Angiosarcoma) 09/01/2006 - "Complete remission of relapsing high-grade angiosarcoma with single-agent metronomic trofosfamide." 09/01/2006 - "We report on a case from our clinic, in which a complete response with oral trofosfamide was achieved in a patient suffering from relapsed high-grade angiosarcoma metastasizing to the liver and lung" 11/15/2003 - "METHODS: Six patients with advanced and pretreated but progressive, malignant vascular tumors (5 angiosarcomas and 1 hemangioendothelioma) received a combination of pioglitazone (45 mg per day orally) plus rofecoxib (25 mg per day orally) and, after 14 days, trofosfamide (3 x 50 mg per day orally)" Get all the results and reference details, order at left...
42 Diseases and 53 more articles analyzed in the Research Interface, order at left...

Related Drugs and Biologics

1.	Ifosfamide
2.	pioglitazone (Actos)
3.	Etoposide (VP 16)
4.	Fluorouracil (Carac)
5.	Hormones
6.	Cyclophosphamide (Cytoxan)
7.	trofosfamide
8.	rofecoxib (Vioxx)
9.	Doxorubicin (Adriamycin)
10.	Vincristine (Oncovin)
53 Drugs and Important Bio-Agents and 33 more articles analyzed in the Research Interface, order at left...

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)
2.	Palliative Care (Palliative Medicine)
3.	Heterologous Transplantation (Xenotransplantation)
4.	Pleurodesis
5.	Salvage Therapy
6 Therapies and Procedures and 16 more articles analyzed in the Research Interface, order at left...

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