3,7,12-trihydroxycoprostanic acid

Also Known As:

3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholestanoic acid; 3 alpha,7 alpha,12 alpha-trihydroxycoprostanic acid; 5-THCA; (3 alpha,5 beta,7 alpha,12 alpha)-3,7,12-trihydroxycholestane-5-carboxylic acid

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Polycyclic Compounds: 6
- Fused-Ring Compounds
  - Steroids: 70059
    - Bile Acids and Salts: 11432
      - Cholic Acids: 14
        3,7,12-trihydroxycoprostanic acid: 2
    - Cholanes
      - Cholic Acids: 14
        3,7,12-trihydroxycoprostanic acid: 2

Related Diseases

1.	Peroxisomal Disorders (Peroxisomal Disorder) 01/01/1991 - "Defective side chain oxidation also occurs in peroxisomal disorders but this time it leads to accumulation of C27 bile acids such as 3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholestanoic acid (trihydroxycoprostanic acid, THCA). "
2.	Hepatoblastoma 12/01/1993 - "We have examined the ability of HepG2 human hepatoblastoma cells and 7800 C1 Morris rat hepatoma cells to convert 3 alpha, 7 alpha, 12 alpha-trihydroxy-5 beta-cholestanoic acid (THCA) and 3 alpha, 7 alpha-dihydroxy-5 beta-cholestanoic acid (DHCA) to cholic acid and chenodeoxycholic acid, respectively. "
3.	Hepatocellular Carcinoma (Hepatoma) 12/01/1993 - "We have examined the ability of HepG2 human hepatoblastoma cells and 7800 C1 Morris rat hepatoma cells to convert 3 alpha, 7 alpha, 12 alpha-trihydroxy-5 beta-cholestanoic acid (THCA) and 3 alpha, 7 alpha-dihydroxy-5 beta-cholestanoic acid (DHCA) to cholic acid and chenodeoxycholic acid, respectively. "

Related Drugs and Biologics

1.	Acids
2.	Cholic Acid
3.	Chenodeoxycholic Acid (Chenix)
4.	Bile Acids and Salts (Bile Acids)