|1.||Dyle, Michael C: 3 articles (10/2015 - 05/2014)|
|2.||Ebert, Scott M: 3 articles (10/2015 - 05/2014)|
|3.||Adams, Christopher M: 3 articles (10/2015 - 05/2014)|
|4.||Friedman, Mendel: 3 articles (04/2015 - 01/2003)|
|5.||Dierdorff, Jason M: 2 articles (10/2015 - 05/2014)|
|6.||Bullard, Steven A: 2 articles (10/2015 - 05/2014)|
|7.||Bongers, Kale S: 2 articles (10/2015 - 05/2014)|
|8.||Fox, Daniel K: 2 articles (10/2015 - 05/2014)|
|9.||Tiralongo, Joe: 1 article (11/2015)|
|10.||Akter, Raushanara: 1 article (11/2015)|
03/14/2012 - "The study provides the first evidence that tomatidine significantly suppresses the activity of ACAT and leads to reduction of atherogenesis."
03/14/2012 - "This study examined whether tomatidine, the aglycone of tomatine, which is a major tomato glycoalkaloid, also shows similar inhibitory effects on cholesterol ester (CE) accumulation in human monocyte-derived macrophages (HMDM) and atherogenesis in apoE-deficient mice. "
03/14/2012 - "Tomatidine, a tomato sapogenol, ameliorates hyperlipidemia and atherosclerosis in apoE-deficient mice by inhibiting acyl-CoA:cholesterol acyl-transferase (ACAT)."
|3.||Body Weight (Weight, Body)
01/01/2003 - "In non-pregnant mice, observed ratios of % liver weights to body weights (%LW/BWs) were significantly greater than those of the control values as follows (all values in % vs matched controls+/-S.D.): solanidine, 25.5+/-13.2; solasodine 16.8+/-12.0; and tomatidine, 6.0+/-7.1. "
01/01/2003 - "For pregnant mice (a) body weight gains were less with the algycones than with controls: solanidine, -36.1+/-14.5; solasodine, -17.9+/-14.3; tomatidine, -11.9+/-18.1; (b) litter weights were less than controls: solanidine, -27.0+/-17.1; solasodine, -15.5+/-16.8; tomatidine, no difference; (c) the %LTW/BW ratio was less than that of the controls and was significant only for solasodine, -8.7+/-13.7; and (d) the average weight of the fetuses was less than the controls: solanidine, -11.2+/-15.2; solasodine, -11.4+/-9.4; tomatidine, no difference. "
03/01/2014 - "The aim of this study was to investigate for the first time whether both extracts from tomato plant (Lycopersicon esculentum Mill.) leaves and their isolated steroidal alkaloids (tomatine and tomatidine) afford neuroprotective effect against glutamate-induced toxicity in SH-SY5Y neuroblastoma cells and to elucidate the mechanisms underlying this protection. "
05/25/2013 - "Tomatidine is found to possess anti-inflammatory properties and may serve as a chemosensitizer in multidrug-resistant tumor cells. "
05/25/2013 - "However, the effect of tomatidine on cancer cell metastasis remains unclear. "
04/18/2012 - "Structure-activity relationships of α-, β(1)-, γ-, and δ-tomatine and tomatidine against human breast (MDA-MB-231), gastric (KATO-III), and prostate (PC3) cancer cells."
07/09/2008 - "Here, we demonstrate that tomatidine acts as an anti-inflammatory agent by blocking NF-kappaB and JNK signaling, and may possibly be developed as a useful agent for the chemoprevention of cancer or inflammatory diseases."
03/01/2001 - "Here we examined the ability of steroidal alkaloids of plant origin, namely the Veratrum sp. alkaloid cyclopamine and the Lycopersicon sp. alkaloid tomatidine, to act as potent and effective chemosensitizers in multidrug resistant tumor cells. "
|2.||Apolipoproteins E (ApoE)
|6.||Acyl Coenzyme A (Acyl CoA)
|9.||Glutamic Acid (Glutamate)