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tomaymycin

structure

Also Known As:

2-ethylidene-1,2,3,10,11,11a-hexahydro-8-hydroxy- 7,11-dimethoxy-5H-pyrrolo(2,1-c)(1,4)benzodiazepin- 5-one

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzazepines: 5
      - Benzodiazepines: 8452
        Benzodiazepinones
        tomaymycin: 2

Experts

1.	Aubert, Catherine: 1 article (01/2021)
2.	Lavisse, Mélanie: 1 article (01/2021)
3.	Roy, Sebastien: 1 article (01/2021)

Related Diseases

1.	Neoplasms (Cancer) 01/01/2021 - "Antibody drug conjugates (ADCs) are one of the most promising technologies to treat cancer as they combine the specificity of an antibody with the high potency of a cytotoxic molecule such as tomaymycin derivatives, which are DNA-interactive antitumor antibiotics previously isolated from bacterial broth. "
2.	Leukemia P388 03/01/1985 - "As analogues of pyrrolo[2,1-c][1,4]benzodiazepine antitumor antibiotics, such as anthramycin and tomaymycin, several benzo[1,4]diazepine imines and carbinolamine ethers were prepared and tested in vivo against P388 leukemia. "

Related Drugs and Biologics

1.	Anti-Bacterial Agents (Antibiotics)
2.	Immunoconjugates (Immunoconjugate)
3.	Imines
4.	Ethers
5.	DNA (Deoxyribonucleic Acid)
6.	Benzodiazepines
7.	Anthramycin (Antramycin)