22-hydroxycholesterol

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8 relevant articles (0 outcomes, 0 trials/studies) found for this Bio-Agent

Also Known As:

(22R)-22-hydroxycholesterol; 22(R)OH cholesterol; 22-hydroxycholesterol, (3beta,20R,22R)-isomer; 22-hydroxycholesterol, (3beta,20R,22S)-isomer; 22-hydroxycholesterol, (3beta,22R)-isomer; 22-hydroxycholesterol, (3beta,22S)-isomer; 22R-hydroxycholesterol; 22S-hydroxycholesterol; cholest-5-ene-3beta,22-diol

Bio-Agent Context: Research Results

Polycyclic Compounds: 58

Hydroxycholesterols: 1

22-hydroxycholesterol: 8

Cholestenes

Cholesterol: 31203

Hydroxycholesterols: 1

22-hydroxycholesterol: 8

Hydroxycholesterols: 1

22-hydroxycholesterol: 8

Experts

1.	Lecanu, L: 1 article (08/2007)
2.	Han, Z: 1 article (08/2007)
3.	Xu, J: 1 article (08/2007)
4.	Papadopoulos, V: 1 article (08/2007)
5.	Yao, Z-X: 1 article (08/2007)
6.	Greeson, J: 1 article (08/2007)

Related Diseases

1.	Alzheimer Disease (Alzheimer's Disease) 01/01/2006 - "In Alzheimer's disease pathology neurosteroid biosynthesis is altered and a decrease in the intermediate 22R-hydroxycholesterol levels is observed" 01/01/2004 - "In conclusion, these results suggest that spirost-5-en-3-ol naturally occurring derivatives of 22R-hydroxycholesterol might offer a new approach for Alzheimer's disease therapy." 12/01/2002 - "22R-hydroxycholesterol, a steroid intermediate in the pathway of pregnenolone formation from cholesterol, was found at lower levels in Alzheimer's disease (AD) hippocampus and frontal cortex tissue specimens compared to age-matched controls" 08/24/2007 - "Recently, we have shown that 22R-hydroxycholesterol, a steroid intermediate in the pathway of pregnenolone formation from cholesterol, is present at lower levels in Alzheimer's disease (AD) hippocampus and frontal cortex tissue specimens than in age-matched controls, and that this substance protects against cell death induced by amyloid beta-peptide in both rat sympathetic nerve pheochromocytoma (PC12) and differentiated human Ntera2/D1 teratocarcinoma neurons" Get all the results and reference details, order at left...
2.	Teratocarcinoma 08/24/2007 - "Herein we report that 22R-hydroxycholesterol inhibits the proliferation of human Ntera2/D1 teratocarcinoma precursor cells (NT2) and induces these cells to differentiate into "neuron-like" or "astrocyte-like" cells" 08/24/2007 - "22R-Hydroxycholesterol induces differentiation of human NT2 precursor (Ntera2/D1 teratocarcinoma) cells." 12/01/2002 - "22R-hydroxycholesterol was found to protect, in a dose-dependent manner, against Abeta-induced rat sympathetic nerve pheochromocytoma (PC12) and differentiated human Ntera2/D1 teratocarcinoma (NT2N) neuron cell death" 08/24/2007 - "Recently, we have shown that 22R-hydroxycholesterol, a steroid intermediate in the pathway of pregnenolone formation from cholesterol, is present at lower levels in Alzheimer's disease (AD) hippocampus and frontal cortex tissue specimens than in age-matched controls, and that this substance protects against cell death induced by amyloid beta-peptide in both rat sympathetic nerve pheochromocytoma (PC12) and differentiated human Ntera2/D1 teratocarcinoma neurons" Get all the results and reference details, order at left...
3.	Shock 01/01/1994 - "Heat shock inhibition of steroidogenesis was fully reversed by 22R-hydroxycholesterol (22-OH cholesterol), a cell- and mitochondria-permeant cholesterol analog" 08/01/1996 - "Heat shock inhibition of progesterone synthesis was partially reversed by the cell- and mitochondria-permeant cholesterol analogue, 22R-hydroxycholesterol" Get all the results and reference details, order at left...
4.	Pheochromocytoma 12/01/2002 - "22R-hydroxycholesterol was found to protect, in a dose-dependent manner, against Abeta-induced rat sympathetic nerve pheochromocytoma (PC12) and differentiated human Ntera2/D1 teratocarcinoma (NT2N) neuron cell death" 08/24/2007 - "Recently, we have shown that 22R-hydroxycholesterol, a steroid intermediate in the pathway of pregnenolone formation from cholesterol, is present at lower levels in Alzheimer's disease (AD) hippocampus and frontal cortex tissue specimens than in age-matched controls, and that this substance protects against cell death induced by amyloid beta-peptide in both rat sympathetic nerve pheochromocytoma (PC12) and differentiated human Ntera2/D1 teratocarcinoma neurons" Get all the results and reference details, order at left...
5.	Infection 08/01/1997 - "Stimulation of Leydig cell testosterone production with hCG or 22R-hydroxycholesterol (22ROHC) significantly reduced in infected rams at both 28 and 58 d after infection as well as in scrotal-insulated rams on Day 58" Get all the results and reference details, order at left...
6 Diseases and 8 more articles analyzed in the Research Interface, order at left...

Related Drugs and Biologics

1.	Cholesterol
2.	Pregnenolone
3.	Testosterone (Sustanon)
4.	Sphingomyelin Phosphodiesterase (Sphingomyelinase)
5.	Progesterone
6.	Amyloid (Amyloid Fibrils)
6 Drugs and Important Bio-Agents and 6 more articles analyzed in the Research Interface, order at left...

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