cortol

RN given refers to (3alpha,5beta,11beta,20S)-isomer

Also Known As:

cortol, (11beta)-isomer; cortol, (3alpha,5alpha,11beta,20S)-isomer; cortol, (3alpha,5beta,11beta,20R)-isomer; cortol, (3beta,5alpha,11beta,20R)-isomer; cortol, (3beta,5beta,11beta,20R)-isomer; 5 beta-pregnane-3 alpha,11 beta,17,20,21-pentol

Networked: 7 relevant articles (2 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Polycyclic Compounds: 6
- Fused-Ring Compounds
  - Steroids: 70059
    - Pregnanes: 9
      - cortol: 7

Experts

1.	Fustinoni, Silvia: 1 article (07/2013)
2.	Mercadante, Rosa: 1 article (07/2013)
3.	Polledri, Elisa: 1 article (07/2013)
4.	Axelson, M: 1 article (05/2013)
5.	Lönn, L: 1 article (05/2013)
6.	Rask, E: 1 article (05/2013)
7.	Simonyte, K: 1 article (05/2013)
8.	Bufa, Anita: 1 article (01/2010)
9.	Bíró, Ildikó: 1 article (01/2010)
10.	Felinger, Attila: 1 article (01/2010)

Related Diseases

1.	Psoriasis (Pustulosis Palmaris et Plantaris) 01/01/1994 - "Quantitative and qualitative analysis of chromatograms in 40 patients and 30 controls permitted assessment of excretion of 17-ketosteroids, hydroxyandrosterone, etiocholanolone, androsterone, dihydroepiandrosterone, beta-cortol compounds, etc., which is important in studies of psoriasis pathogenesis and in assessment of the efficacy of treatment of this and other diseases."
2.	Obesity 04/01/2023 - "In pre-adolescent children with obesity, α-cortol and especially α-cortolone appeared to be excreted more abundantly than β-cortol or β-cortolone. " 03/01/1999 - "There was a significant reduction in the urinary tetrahydrocortisol (THF) +/- 5alpha-THF/tetrahydrocortisone (THE) and the cortol/cortolone ratio in obesity (group A vs. C, 1.06 +/- 0.08 vs. 0.84 +/- 0.04 and 0.41 +/- 0.03 vs. 0.34 +/- 0.03, respectively; both P < 0.05). "
3.	Weight Loss (Weight Reduction) 05/01/2013 - "The ratio of cortisol to cortisone metabolites [(5α-tetrahydrocortisol (5αTHF) + tetrahydrocortisol (THF) + α-cortol)/(tetrahydrocortisone (THE) + α-cortolone)] and the ratio of 5α-THF/THF both decreased after stable weight loss, reflecting a downregulation of the net activities of 11β-HSD type 1 and 5α-reductase. "
4.	Sleep Wake Disorders 07/15/2013 - "Cortisol, cortisone, and melatonin (CORTol, CORTone, and MELA, respectively) are hormones related to stress and sleep disorders. "
5.	Hirsutism 01/01/1979 - "Urinary unconjugated cortisol, total 17-oxogenic steroids and cortisol metabolites (THF, allo-THF, THE, cortol and cortolone) were measured in 90 normal women and in 90 women with idiopathic hirsutism of comparable age group. "

Related Drugs and Biologics

1.	Etiocholanolone
2.	Androsterone
3.	17-Ketosteroids (17 Ketosteroids)
4.	cortolone
5.	Tetrahydrocortisone
6.	Tetrahydrocortisol
7.	Hydrocortisone (Cortisol)
8.	Cortisone
9.	Steroids
10.	Pregnanetriol