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sapropterin (tetrahydrobiopterin)

RN given refers to parent cpd; co-factor required for catalytic activity of nitric oxide synthases
Also Known As:
tetrahydrobiopterin; THBP; 1-butanone, 1-(2,4,5-trihydroxyphenyl); 2',4',5'-trihydroxybutyrophenone; 2,4,5-trihydroxybutyrophenone; 5,6,7,8-erythro-tetrahydrobiopterin; 5,6,7,8-tetrahydro-L-erythrobiopterin; 5,6,7,8-tetrahydrobiopterin; 5,6,7,8-tetrahydrobiopterin, (S-(R*,S*))-isomer; 5,6,7,8-tetrahydrodictyopterin; 6R-BH4; 6R-L-erythro-5,6,7,8-tetrahydrobiopterin; D-threo-tetrahydrobiopterin; kuvan; phenylalanine hydroxylase cofactor; sapropterin dihydrochloride; tetrahydro-6-biopterin; trihydroxybutyrophenone
Networked: 887 relevant articles (53 outcomes, 100 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1. Blau, Nenad: 35 articles (01/2021 - 02/2002)
2. Channon, Keith M: 29 articles (12/2018 - 03/2004)
3. Thöny, Beat: 17 articles (09/2021 - 01/2004)
4. Blau, N: 15 articles (01/2014 - 01/2000)
5. Muntau, Ania C: 14 articles (01/2021 - 12/2002)
6. Shintaku, Haruo: 10 articles (01/2021 - 05/2007)
7. Burton, Barbara K: 9 articles (01/2021 - 11/2008)
8. Feillet, François: 9 articles (01/2019 - 08/2007)
9. Trefz, Friedrich K: 9 articles (01/2017 - 02/2002)
10. Alp, Nicholas J: 9 articles (10/2011 - 03/2004)

Related Diseases

1. Phenylketonurias (Phenylketonuria)
2. Reperfusion Injury
3. Fibrosis (Cirrhosis)
4. Atherosclerosis
5. Myocardial Infarction

Related Drugs and Biologics

1. Phenylalanine (L-Phenylalanine)
2. sapropterin (tetrahydrobiopterin)
3. Phenylalanine Hydroxylase (Phenylalanine 4 Monooxygenase)
4. GTP Cyclohydrolase (GTP Cyclohydrolase I)
5. Nitric Oxide Synthase (NO Synthase)
6. Enzymes
7. Nitric Oxide (Nitrogen Monoxide)
8. Superoxides (Superoxide)
9. Acetylcholine (Acetylcholine Chloride)
10. Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)

Related Therapies and Procedures

1. Therapeutics
2. Aftercare (After-Treatment)
3. Pancreas Transplantation
4. Intravenous Administration
5. Diet Therapy (Therapy, Diet)