|1.||Zhang, Cui: 2 articles (11/2014 - 01/2013)|
|2.||Lu, Ying: 2 articles (11/2014 - 01/2013)|
|3.||Tong, Qian-Qian: 2 articles (11/2014 - 01/2013)|
|4.||Liao, Yue-Ling: 2 articles (01/2014 - 06/2012)|
|5.||Zhang, Chen: 2 articles (01/2014 - 06/2012)|
|6.||Wei, Hong-Chang: 2 articles (01/2014 - 06/2012)|
|7.||Guo, Wei: 2 articles (01/2014 - 06/2012)|
|8.||Kang, Tian-Ji: 1 article (11/2014)|
|9.||Qu, Chao: 1 article (11/2014)|
|10.||Zhou, Ya-Jie: 1 article (11/2014)|
01/01/2010 - "Consequently, our findings indicate that TF plays an important role in the development of anoxia-reoxygenation injury of HUVECs, stachydrine ameliorates HUVECs injury induced by anoxia-reoxygenation and its putative mechanisms are related to inhibition of TF expression."
01/01/2010 - "Stachydrine, a major constituent of the Chinese herb leonurus heterophyllus sweet, ameliorates human umbilical vein endothelial cells injury induced by anoxia-reoxygenation."
01/01/2010 - "Our study aimed to investigate the role of stachydrine in human umbilical vein endothelial cells (HUVECs) injury induced by anoxia-reoxygenation. "
01/01/2010 - "HUVECs in the control group were exposed to normoxia for 5 hours, while in all A/R groups, HUVECs underwent 3 hours anoxia followed by 2 hours reoxygenation, and HUVECs in the 4 A/R+stachydrine groups were treated with 10(-8) M, 10(-7) M, 10(-6) M and 10(-5) M (final concentration) of stachydrine respectively. "
01/01/2010 - "However, in stachydrine treated groups, TF expression was inhibited at both mRNA and protein levels, while the declined cell viability and SOD, GSH-PX, NO as well as the enhanced LDH, MDA and ET-1 levels occurred during anoxia-reoxygenation were ameliorated and reversed effectively (p < 0.05 to 0.01 versus A/R group). "
06/01/2012 - "[Effect of Leonurus stachydrine on myocardial cell hypertrophy]."
06/01/2012 - "To investigate the effects of Leonurus stachydrine on myocardial cell hypertrophy induced by angiotensin II in rats. "
01/01/2014 - "The aim of the present study was to investigate the effects of stachydrine (STA), a major constituent of Leonurus heterophyllus sweet, on norepinephrine (NE) induced hypertrophy and the changes of calcium transients in neonatal rat cardiomyocytes. "
01/01/2014 - "Effects of stachydrine on norepinephrine-induced neonatal rat cardiac myocytes hypertrophy and intracellular calcium transients."
|3.||Uterine Hemorrhage (Uterine Bleeding)
01/09/2013 - "The purpose of this study was to determine the Th1/Th2/Th17/Treg paradigm in uterine bleeding of RU486-induced abortion mice and to elucidate the immunopharmacologic effects of stachydrine hydrochloride on inducing the Th1/Th2/Th17/Treg paradigm in reducing the uterine bleeding volume in RU486-induced abortion mice. "
01/09/2013 - "The Th1/Th2/Th17/Treg paradigm induced by stachydrine hydrochloride contributed to the reduction in uterine bleeding in RU486-induced abortion mice."
01/09/2013 - "The volume of uterine bleeding during RU486-induced abortion was reduced significantly after stachydrine hydrochloride administration. "
01/09/2013 - "The Th1/Th2/Th17/Treg paradigm induced by stachydrine hydrochloride reduces uterine bleeding in RU486-induced abortion mice."
01/09/2013 - "To evaluate the effect of stachydrine hydrochloride in reducing uterine bleeding via regulation of the Th1/Th2/Th17/Treg paradigm, pregnant mice were treated with RU486 (1.5mg/kg) and/or stachydrine hydrochloride (2.5mg/kg, 5mg/kg, and 10mg/kg). "
|4.||Prostatic Neoplasms (Prostate Cancer)
01/01/2012 - "In vitro anticancer activity of stachydrine isolated from Capparis decidua on prostate cancer cell lines."
01/01/2012 - "Studies revealed a dose dependent decrease in expression of mRNA, and protein levels were observed in stachydrine-treated human prostate cancer cells (PC-3 and LNcaP) as detected by reverse transcriptase-polymerase chain reaction (RT-PCR). "
01/01/2013 - "Effect of stachydrine on endoplasmic reticulum stress-induced apoptosis in rat kidney after unilateral ureteral obstruction."
11/01/2014 - "We studied the effect of stachydrine on the expression of caspase-12 and 9 in rats with unilateral ureteral obstruction. "
11/01/2014 - "The effect of stachydrine on the expression of caspase-12 in rats with unilateral ureteral obstruction."
|1.||Messenger RNA (mRNA)
|2.||RNA-Directed DNA Polymerase (Reverse Transcriptase)
|7.||Mifepristone (RU 486)
|10.||Quaternary Ammonium Compounds (Ammonium)