Piromen

07/01/1953 - "Piromen therapy in asthma; functional and clinical studies."
07/01/1952 - "Sudden death from bronchial asthma following injection of pyromen; case report."

12/01/1953 - "A study on the use of piromen for the treatment of duodenal ulcer in man."

09/01/1955 - "Effect of piromen on spasticity in cases of spinal cord injury."
05/01/1979 - "Spinal cord transection: a quantitative analysis of elements of the connective tissue matrix formed within the site of lesion following administration of piromen, cytoxan or trypsin."
01/01/1980 - "Qualitative and quantitative effects of ACTH, piromen, cytoxan and isobutyl-2-cyanoacrylate treatments following spinal cord transection in rats."

07/01/1982 - "Intrahypothalamic injection of piromen increased metabolism and decreased cutaneous temperatures which led to fever in rats at Ta 8-30 degrees C. "
06/01/1989 - "The fever induced by intrahypothalamic injection of piromen or SS-14, as well as that induced by intraperitoneal injection of piromen, was antagonized by pretreatment of the hypothalamus with a SS-14 receptor antagonist (0.1 ng in 1.0 microliter) in rats. "
06/01/1989 - "Furthermore, the fever induced by intrahypothalamic injection of piromen, but not SS-14, was antagonized by depletion of hypothalamic SS levels with an intraperitoneal dose of cysteamine (30 mg/kg). "
04/01/1955 - "The fever induced by pyromen or dextran was found to be markedly suppressed when cortisone was administered in liberal amounts (25 mg. twice daily) for 3 days prior to the challenge. "
07/01/1982 - "The data indicate that a norepinephrine- cyclic AMP link occurs in the hypothalamic pathways which mediate the piromen-induced or the prostaglandin E2-induced fever in rats."

01/01/1975 - "The changes of the glial-mesenchymal scar after administration of Piromen, reported in the literature, were on the whole confirmed."
01/01/1975 - "In the present work the effect of Piromen is studied on the formation of the glial-mesenchymal scar in the experimentally injuried cortex of hamsters. "
01/01/1975 - "[The effect of piromen on the flial-mesenchymal scar in the cortex of hamsters]."
01/01/1980 - "Statistical analysis of the quantitative data indicated that Piromen and Cytoxan, respectively, were significantly more effective than the other treatments in promoting regeneration of nerve fibers into the scar. "
05/01/1979 - "Giving cytoxan or piromen did not result in any qualitative alteration of the scar matrix as evidenced by electron microscopy. "