|1.||Lizard, Gérard: 11 articles (07/2015 - 08/2002)|
|2.||Lee, Jung Wha: 5 articles (01/2014 - 02/2009)|
|3.||Riedinger, Jean-Marc: 4 articles (07/2015 - 01/2009)|
|4.||Prunet, Céline: 4 articles (06/2005 - 08/2002)|
|5.||Néel, Dominique: 4 articles (06/2005 - 08/2002)|
|6.||Lemaire-Ewing, Stéphanie: 4 articles (06/2005 - 08/2002)|
|7.||Delmas, Dominique: 3 articles (07/2015 - 09/2011)|
|8.||Nury, Thomas: 3 articles (07/2015 - 09/2011)|
|9.||Vejux, Anne: 3 articles (07/2015 - 06/2005)|
|10.||Rodriguez, Ignacio R: 3 articles (01/2015 - 04/2012)|
09/01/2007 - "Here, we present preliminary, but promising results for the bacterial biodegradation of 7-ketocholesterol, the main accumulator of foam cells associated with atherosclerosis. "
10/10/2014 - "CD36-dependent 7-ketocholesterol accumulation in macrophages mediates progression of atherosclerosis in response to chronic air pollution exposure."
07/01/2012 - "We find significant accumulation of three oxysterols, 7α-hydroxycholesterol, 7β-hydroxycholesterol, and 7-ketocholesterol, in mouse aortas of dyslipidemic ApoE⁻/⁻ mice at the early stage of atherosclerosis. "
01/01/2010 - "These data demonstrate that 7-ketocholesterol induces endothelial dysfunction without cell death that may contribute to early events in atherosclerosis."
06/01/2005 - "Oxysterols, and particularly 7-ketocholesterol, appear to be strongly involved in the physiopathology of atherosclerosis. "
|2.||Atherosclerotic Plaque (Atheroma)
07/28/2013 - "7-Ketocholesterol (7-KC)-induced apoptosis of macrophages is considered a key event in the development of human atheromas. "
01/01/2009 - "Among the oxysterols accumulating in atherosclerotic plaque, 7-ketocholesterol (7KC) is a potent apoptotic inducer, which favours myelin figure formation and polar lipid accumulation. "
09/11/2007 - "Expression of 7-ketocholesterol was increased in the fibrous caps of thin-cap atheroma compared with thick-cap atheroma. "
06/01/2004 - "In particular, 7-oxocholesterol has been found in plasma from cardiac patients and atherosclerotic plaque. "
04/15/2002 - "7-Ketocholesterol (7KC) is a major oxysterol found in atherosclerotic plaque and is believed to be derived both endogenously and exogenously (from the diet). "
|3.||Coronary Artery Disease (Coronary Atherosclerosis)
08/01/2009 - "The aim of this study was to clarify the clinical significance of serum 7-ketocholesterol concentrations (s-7KCHO) in the progression of coronary atherosclerosis. "
07/01/2000 - "Impact of baseline level of 7-ketocholesterol on the rate of coronary reintervention in coronary artery disease patients--results of an observational study with questionnaire-based follow up."
08/01/2009 - "Clinical significance of serum 7-ketocholesterol concentrations in the progression of coronary atherosclerosis."
07/01/2000 - "We failed to find a significant relation between 7-ketocholesterol and coronary artery disease, though there is a trend of such relation in patients who undergo PTCA, evidenced by a slightly higher number of repeated revascularizations among patients with high 7-ketocholesterol. "
07/01/2000 - "We measured plasma level of 7-ketocholesterol, malondialdehyde, total cholesterol, HDL cholesterol, triglycerides, erythrocyte activity of superoxide dismutase in 233 patients who previously underwent coronary angiography for diagnosis of coronary artery disease. "
01/01/2013 - "7-Ketocholesterol induces inflammation and angiogenesis in vivo: a novel rat model."
04/01/2012 - "In this study we demonstrate that sterculic acid is a potent inhibitor of endoplasmic reticulum (ER) stress and related inflammation caused by 7-ketocholesterol (7KCh). "
07/01/2012 - "We tested the hypothesis that oxysterols 25-hydroxycholesterol (25-OHC) and 7-ketocholesterol (7-ketoC) promote placental trophoblast inflammation, and determined the mechanisms involved. "
07/01/2008 - "Since atherosclerosis is associated with the presence of apoptotic cells and with oxidative and inflammatory processes, the ability of some oxysterols, especially 7-ketocholesterol and 7beta-hydroxycholesterol, to trigger cell death, activate inflammation, and modulate lipid homeostasis is being extensively studied, especially in vitro. "
03/01/2007 - "We conclude that in confluent primary porcine RPE cells, 24-hydroxycholesterol, 25-hydroxycholesterol, and 7-ketocholesterol are potent inducers of oxidation and inflammation."
12/01/2001 - "In the present study, we measured not only 7-hydroperoxycholesterols but also oxysterols (7 alpha- and 7 beta-hydroxycholesterol, 7 alpha-OH, and 7 beta-OH) and 3 beta-hydroxycholest-5-en-7-one (7-keto) in the brains of rats that underwent either a sham operation (control), hypoxia, or CO inhalation (1005 ppm) at 37 degrees C for 90 min followed by 48 h of recovery. "
|1.||cholest-5-en-3 beta,7 alpha-diol
|7.||salicylhydroxamic acid (SHAM)
|10.||oxidized low density lipoprotein