epitiostanol

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5 relevant articles (0 outcomes, 0 trials/studies) found for this Bio-Agent

Description: used in therapy of advanced breast cancer; structure

Also Known As:

10275-S; 2 alpha,3 alpha-epithio-5 alpha-androstan-17 beta-ol; Thiodrol; epithiostanol; androstan-17-ol, 2,3-epithio-, (2 alpha,3 alpha,5 alpha,17 beta)-

Bio-Agent Context: Research Results

Polycyclic Compounds: 58

Related Diseases

1.	Neoplasms (Cancer) 04/01/1995 - "The incidence of apoptosis revealed by the nick end labeling method reached its maximum, about threefold the control level, on the 3rd day of epitiostanol treatment compared with control tumors (P < 0.01)" 04/01/1995 - "BrdU-labeled apoptotic bodies were detected in the tumors on the 3rd day in epitiostanol-treated rats that received a 6-hr bolus of BrdU before sacrifice.(ABSTRACT TRUNCATED AT 250 WORDS)" 12/01/1977 - "A comparison of these findings to those obtained with earlier generations suggests that TPDMT-4 tumors became less sensitive to the antitumor effect of epitiostanol and were able to grow at lower hormone levels with succeeding generations" 12/01/1977 - "Under similar conditions ovariectomy caused tumor regression immediately, and epitiostanol, the parent steroid of mepitiostane, significantly suppressed tumor growth when given in 3 injections/week of 0.5 mg s.c" 05/01/1976 - "Tumors regressed immediately after ovariectomy or after the start of 10275-S treatment and after approximately the 10th day of testosterone treatment" Get all the results and reference details, order at left...
2.	Breast Neoplasms (Breast Cancer) 07/01/1988 - "A case of advanced breast cancer successfully treated with combined tamoxifen and epitiostanol]" Get all the results and reference details, order at left...
2 Diseases and 5 more articles analyzed in the Research Interface, order at left...

Related Drugs and Biologics

1.	Tamoxifen
2.	Testosterone Propionate
3.	Testosterone (Sustanon)
4.	Progesterone
5.	Hormones
6.	Estrogens (Estrogen)
7.	DNA (Deoxyribonucleic Acid)
8.	Bromodeoxyuridine (BrdU)
9.	anthracene
10.	mepitiostane
10 Drugs and Important Bio-Agents and 5 more articles analyzed in the Research Interface, order at left...

Related Therapies and Procedures

1.	Ovariectomy (Oophorectomy)
1 Therapies and Procedures and 2 more articles analyzed in the Research Interface, order at left...

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