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platinum ethylenediamine dichloride

Also Known As:

PtCl2(ethane-1,2-diamine); cis-dichloro(ethylenediamine)platinum II; dichloro(1,2-ethanediamine-N,N')platinum; ethylenediamine platinum dichloride

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Organometallic Compounds: 64
  - Organoplatinum Compounds
    - platinum ethylenediamine dichloride: 3

Related Diseases

1.	Plasmacytoma 03/01/1983 - "The pharmacokinetics of the antitumor agents ethylenediamine platinum dichloride and cisplatin have been investigated in mice bearing the ADJ/PC6 plasma cell tumor after therapeutic doses of these agents, labeled either with 191Pt or in the ligand with 14C. "
2.	Neoplasms (Cancer) 09/10/1985 - "Characterization of the adducts produced in DNA by the cancer chemotherapeutic drug cis-diamminedichloroplatinum(II) and a radiolabeled analogue, [3H]-cis-dichloro(ethylenediamine)platinum(II) ([3H]-cis-DEP) was recently reported [Eastman, A. "
3.	Hyperthermia 01/01/1993 - "Despite the observation that 45 degrees C hyperthermia increased the intracellular uptake of the DDP analog [3H]-cis-dichloro(ethylenediamine)platinum(II) (DEP) during a 1-h exposure by 155% +/- 55% (P = 0.02), median-effect analysis indicated only cytotoxic additivity (combination index at the level of 50% cell kill, 0.96 +/- 0.25). "

Related Drugs and Biologics

1.	Cisplatin (Platino)
2.	1-(2-(dodecyloxy)ethyl)pyrrolidine hydrochloride (DEP)
3.	Ligands
4.	DNA (Deoxyribonucleic Acid)
5.	Antineoplastic Agents (Antineoplastics)
6.	PC6 extract (PC6)