ophiobolins

tricyclic sesterterpenes, include ophiobolins A,B,C,D,F; RN in Chemline for ophiobolin A: 4611-05-6; RN for ophiobolin B: 5601-74-1; RN for ophiobolin C: 19022-51-6; structure

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Cai, Jian: 1 article (02/2022)
2.	Chen, Siqiang: 1 article (02/2022)
3.	Li, Kunlong: 1 article (02/2022)
4.	Liu, Yonghong: 1 article (02/2022)
5.	Pang, Xiaoyan: 1 article (02/2022)
6.	Zhang, Xinya: 1 article (02/2022)
7.	Zhou, Xuefeng: 1 article (02/2022)
8.	Zhu, Yiguang: 1 article (02/2022)
9.	Deng, Zixin: 1 article (01/2019)
10.	Hong, Kui: 1 article (01/2019)

Related Diseases

1.	Neoplasms (Cancer) 01/01/2019 - "Ophiobolins are sesterterpene compounds with a distinct tricyclic 5-8-5 ring and have presented anti-cancer activities. "
2.	Leukemia 11/26/2013 - "Ophiobolins A, B, C and K displayed bioactivity towards leukemia cells with induction of apoptosis at nanomolar concentrations. " 11/26/2013 - "Bio-activity and dereplication-based discovery of ophiobolins and other fungal secondary metabolites targeting leukemia cells."
3.	Infections 04/01/2009 - "Unlike strains from mainly infection-related samples, largely from Europe, neither ophiobolins G and H nor austins were detected in the Canadian strains of A. "
4.	Renal Cell Carcinoma (Grawitz Tumor) 02/15/2022 - "The pharmacological mechanisms of some representative lead compounds are well studied, revealing that they have important medicinal potentials, such as piericidins with anti-renal cell cancer effects, azalomycins with anti-MRSA activities, and ophiobolins as antineoplastic agents. "

Related Drugs and Biologics

1.	Antineoplastic Agents (Antineoplastics)