|1.||Itoh, Z: 2 articles (04/2007 - 07/2000)|
|2.||Kleibeuker, J H: 2 articles (08/2001 - 01/2000)|
|3.||van Gorkom, B A: 2 articles (08/2001 - 01/2000)|
|4.||de Vries, E G: 2 articles (08/2001 - 01/2000)|
|5.||Karrenbeld, A: 2 articles (08/2001 - 01/2000)|
|6.||Hwang, In Young: 1 article (09/2015)|
|7.||Jeong, Choon Sik: 1 article (09/2015)|
|8.||Ooi, Kazuya: 1 article (06/2015)|
|9.||Yokoyama, Satoshi: 1 article (06/2015)|
|10.||Yamate, Yurika: 1 article (06/2015)|
01/01/2011 - "Sennoside A is well known to induce diarrhea. "
07/01/2000 - "In sennoside-induced diarrhea, loperamide and CP improved stool consistency and this was accompanied by reduced fecal moisture and frequency of diarrhea. "
10/01/1993 - "The aim of this study was to investigate whether 5-hydroxytryptamine (serotonin, 5-HT) is involved in the mediation of sennoside-induced colonic fluid secretion and diarrhea. "
02/27/2014 - "When pretreated with indomethacin, sennoside A neither decreased the AQP3 expression nor induced diarrhea. "
07/01/2000 - "Sennoside and carboxymethylcellulose sodium (CMC-Na) increased fecal water content and induced diarrhea at lower doses than that which enhanced stool frequency. "
|2.||Postoperative Nausea and Vomiting (PONV)
09/01/2004 - "This randomized, double-blinded, placebo controlled study evaluated the efficacy of OTFC [normal dose (ND) = 10-15 microg x kg(-1) or low dose = 100 microg] compared with placebo in the prevention of postoperative agitation; and the efficacy of ondansetron (0.1 mg x kg(-1) to 4 mg) compared with placebo to reduce PONV associated with OTFC. "
04/01/2007 - "It is suggested that mitemcinal may be a novel therapeutic agent for constipation that enables easier control of the timing of defecation because of the early onset and short duration of its action, compared with sennoside."
08/01/2010 - "Before the patient develops opioid-induced constipation, preventive action should be conducted, such as using drug combinations (e.g., sennoside and docusate). "
05/01/2000 - "We therefore felt that the optimal dose for creating constipation in the monkeys was 60 mg/kg. We tested the appropriateness of this amitriptyline-induced constipated monkey model by observing the effects of a new laxative, the herbal medicine ND-10 and the commercially available laxative bisacodyl. "
|1.||sennoside A&B (ND 10)
|5.||Serotonin (5 Hydroxytryptamine)
|6.||Polyethylene Glycols (Polyethylene Glycol)
|8.||calcium polycarbophil (polycarbophil)