|1.||Ogawa, Kumiko: 4 articles (08/2007 - 10/2002)|
|2.||Futakuchi, Mitsuru: 4 articles (08/2007 - 10/2002)|
|3.||Shirai, Tomoyuki: 4 articles (08/2007 - 10/2002)|
|4.||Jia, Wei-Dong: 3 articles (02/2012 - 03/2009)|
|5.||Xu, Ge-Liang: 3 articles (02/2012 - 03/2009)|
|6.||Wang, Wei: 3 articles (02/2012 - 03/2009)|
|7.||Tamano, Seiko: 3 articles (01/2005 - 10/2002)|
|8.||Robichová, Sona: 3 articles (06/2004 - 01/2002)|
|9.||Slamenová, Darina: 3 articles (06/2004 - 01/2002)|
|10.||Han, Sheng-Jin: 2 articles (02/2012 - 11/2011)|
|1.||Hepatocellular Carcinoma (Hepatoma)
08/01/2001 - "Transfer of bcl-xs plasmid is effective in preventing and inhibiting rat hepatocellular carcinoma induced by N-nitrosomorpholine."
08/01/2001 - "To examine the effect of the bcl-xs gene on the sequence from hepatic precancerous lesions, foci and neoplastic nodules, to hepatocellular carcinomas, Sprague-Dawley rats were given water containing 175 mg/l N-nitrosomorpholine (NNM) for 8 weeks. "
01/15/2000 - "To investigate the potential use of a bcl-2 antisense oligonucleotide for therapy against hepatocellular carcinoma, we examined the effects of the electroporetic transfer of a bcl-2 antisense oligonucleotide on rat hepatocarcinogenesis induced by N-nitrosomorpholine (NNM). "
01/01/2000 - "We investigated the susceptibility of three inbred strains of rats to the hepatocarcinogen, N-nitrosomorpholine (NNM), to establish a spontaneous metastatic model of hepatocellular carcinoma (HCC). "
01/01/2000 - "Induction of hepatocellular carcinoma with high metastatic potential in WS/Shi rats: discovery of an inbred strain highly susceptible to the liver carcinogen N-nitrosomorpholine."
07/01/1984 - "The results of this study provide quantitative support for the assumption that in vivo formation of N-nitrosomorpholine leads to tumor development."
02/01/2004 - "One hundred sixty-three hepatic tumors 3-12 mm in diameter were induced after 18 weeks of treatment with 0.01 wt/vol% of N-nitrosomorpholine, and 81 of them were evaluated. "
02/01/2004 - "Twelve male rats received N-nitrosomorpholine solution as drinking water to induce hepatic tumors. "
12/01/1990 - "(4) To test for tumor-promoting activity rats received a single dose of N-nitrosomorpholine (250 mg/kg), and subsequently BBR or PB at doses of 2, 10, and 50 mg/kg/day. "
01/01/1989 - "The renal tubular segment from which clear cell tumors originate was investigated in the kidneys of rats treated with N-nitrosomorpholine. "
|3.||Neoplasm Metastasis (Metastasis)
08/01/2007 - "The second experiment focused on the effects of Cx32 disruption on metastasis by HCCs induced by administration of DEN and N-nitrosomorpholine. "
01/15/1997 - "In the present study, it was confirmed that lung metastasis of hepatocellular carcinomas (HCCs) induced in male F344 rats by N-nitrosomorpholine (NNM), given in the drinking water at a dose of 120 ppm for 24 weeks, was significantly enhanced by additional carcinogenic pretreatments and that a single i.p. "
01/01/2005 - "Previously, we established the in vivo lung metastasis model of rat HCC induced by two hepatocarcinogens, diethylnitrosamine (DEN) and N-nitrosomorpholine (NMOR) at a dose of 120 ppm. This model allows us to investigate modifying factors leading to the inhibition of metastasis formation. "
01/01/2005 - "Modification of an in vivo lung metastasis model of hepatocellular carcinoma by low dose N-nitrosomorpholine and diethylnitrosamine."
02/01/2012 - "We conducted an in vivo highly metastatic rat HCC model in female Sprague-Dawley rats induced by diethylnitrosamine and N-nitrosomorpholine to examine the effects of estrogen on HCC metastasis. "
01/01/2002 - "The aim of the present work was to study whether immunization of rats with tularemia live vaccine (TLV) can influence carcinogenic and mutagenic action of N-nitrosomorpholine (NNM). "
01/01/2002 - "Inhibition of carcinogenic and clastogenic effects of N-nitrosomorpholine in rats immunized with tularemia vaccine."
|5.||Glycogen Storage Disease (Glycogenosis)
01/01/1984 - "Systematic studies of the sequence of cellular changes during hepatocarcinogenesis induced predominantly in rats by stop experiments with N-nitrosomorpholine (NNM) led to the following main results and conclusions: The development of hepatocellular tumors is preceded by a multifocal hepatic glycogen storage disease (glycogenosis). "
|3.||Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)
|5.||DNA (Deoxyribonucleic Acid)
|9.||Messenger RNA (mRNA)