2,3-dichloro-alpha-methylbenzylamine

inhibitor of phenethanolamine N-methyltransferase; RN given refers to parent cpd without isomeric designation; structure

Also Known As:

2,3-dichloro-alpha-methylbenzylamine, (+)-isomer; 2,3-dichloro-alpha-methylbenzylamine, (+-)-isomer; 2,3-dichloro-alpha-methylbenzylamine, (-)-isomer; 2,3-dichloro-alpha-methylbenzylamine, hydrochloride; 2,3-dichloro-alpha-methylbenzylamine, hydrochloride, (+-)-isomer; LY 78335; Lilly 78335

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Benzylamines: 10
    - 2,3-dichloro-alpha-methylbenzylamine: 1
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Benzyl Compounds: 2
        Benzylamines: 10
        2,3-dichloro-alpha-methylbenzylamine: 1

Related Diseases

1.	Decapitation 10/01/1985 - "Spontaneous and evoked release of epinephrine was markedly reduced, when rats were pretreated with 2,3-dichloro-alpha-methylbenzylamine, an inhibitor of phenylethanolamine N-methyltransferase, the enzyme catalyzing the formation of epinephrine from norepinephrine, 80 mg/kg i.p., before decapitation. "

Related Drugs and Biologics

1.	Phenylethanolamine N-Methyltransferase
2.	Norepinephrine (Noradrenaline)
3.	Epinephrine (Adrenaline)
4.	Enzymes