1,2-linoleoylphosphatidylcholine

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9 relevant articles (1 outcomes, 0 trials/studies) found for this Bio-Agent

Description: used for premature induction of labor in rabbits; RN given refers to (all Z)-isomer

Also Known As:

1,2-dilinoleoyl-3-glycerophosphocholine; 1,2-linoleoyl-sn-glycero-3-phosphocholine; 1,2-linoleoylphosphatidylcholine, (R-(all Z))-isomer; 1,2-linoleoylphosphatidylcholine, 14C-labeled cpd, (R-(all Z))-isomer; DLPC lipid; dilinoleoyl phosphatidylcholine; dilinoleoyllecithin; dilinoleoylphosphatidylcholine; (all-Z)-4-hydroxy- N,N,N-trimethyl-10-oxo-7-((1-oxo-9,12-octadecadienyl)oxy)-3,5,9-trioxa-4-phosphaheptacosa-18,21-dien-1-aminium, hydroxide, inner salt, 4-oxide

Relationship Network

Bio-Agent Context: Research Results

Lipids: 13315

Membrane Lipids: 339

Phospholipids: 3482

Glycerophosphates: 10

Phosphatidic Acids: 178

Glycerophospholipids: 89

Phosphatidylcholines: 1166

1,2-linoleoylphosphatidylcholine: 9

Related Diseases

1.	Fibrosis (Cirrhosis) 06/01/1999 - "PPC (and its active component dilinoleoylphosphatidylcholine) also oppose hepatic oxidative stress and fibrosis" 04/01/1999 - "The prevention of cirrhosis in alcohol-fed baboons by the administration of a soybean extract-43% to 50% of which was dilinoleoyl-phosphatidylcholine (DLPC) and 24% of which was 1,palmitoyl 2,linoleoyl-phosphatidylcholine (PLPC)-was associated with a significant reduction in the number of stellate cells transformed to myofibroblast-like cells" 01/01/1994 - "CONCLUSIONS: PC prevents alcohol-induced fibrosis and cirrhosis in nonhuman primates, and dilinoleoylphosphatidylcholine appears to be the active species, possibly by promoting collagen breakdown." 09/01/1993 - "Therapy may eventually improve with the use of supernutrients such as S-adenosyl-L-methionine, which replenishes glutathione, restores methylation, and attenuates liver injury, as well as dilinoleoylphosphatidylcholine, which prevents cirrhosis." 05/01/1993 - "On the other hand, phosphatidylcholine, purified from polyunsaturated lecithin, was discovered to oppose the ethanol-induced fibrosis by decreasing the activation of lipocytes to transitional cells, and possibly also by stimulating collagenase activity, an effect for which dilinoleoylphosphatidylcholine, its major phospholipid species, was found to be responsible." Get all the results and reference details, order at left...
2.	Atherosclerosis (Atheroma) 09/01/2000 - "Thus, dilinoleoyl-phosphatidylcholine (the main component of PPC) protects against LDL oxidation, a possible mechanism for its reported anti-atherosclerosis effects." Get all the results and reference details, order at left...
3.	Experimental Liver Neoplasms 11/01/1999 - "METHODS: To determine the responsible phosphatidylcholine species, a Morris hepatoma cell line (RH 7777) was incubated with 100 mumol/L arachidonate supplemented with 20 mumol/L dilinoleoylphosphatidylcholine or 20 mumol/L palmitoyllinoleoylphosphatidylcholine which comprise 42% and 24% of polyenylphosphatidylcholine, respectively or with equivalent amounts of polyenylphosphatidylcholine" Get all the results and reference details, order at left...
4.	Liver Cirrhosis (Hepatic Cirrhosis) 05/01/2007 - "We incorporated the bioactive lipid dilinoleoylphosphatidylcholine (DLPC) into the membrane of liposomes, and then we evaluated its effect on hepatic stellate cell activation and liver fibrosis" Get all the results and reference details, order at left...
5.	Acute Erythroblastic Leukemia (Erythroleukemia) 06/19/1984 - "In contrast, changes in lipid mobility were detected with the spin-label probe when microsomes were first isolated from Friend erythroleukemia cells and subsequently modified by incubation with liposomes composed of either dioleoyl- or dilinoleoylphosphatidylcholine plus bovine liver phospholipid-exchange protein" Get all the results and reference details, order at left...
5 Diseases and 9 more articles analyzed in the Research Interface, order at left...

Related Drugs and Biologics

1.	1- palmitoyl- 2- linoleoylphosphatidylcholine
2.	Phosphatidylcholines (Phosphatidylcholine)
3.	Liposomes (Liposome)
4.	Lecithins
5.	Phospholipid Transfer Proteins
6.	Collagenases (Collagenase)
7.	Methionine (L-Methionine)
8.	Glutathione (Reduced Glutathione)
9.	Collagen
10.	Ethanol (Ethyl Alcohol)
11 Drugs and Important Bio-Agents and 7 more articles analyzed in the Research Interface, order at left...

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