cholesterol alpha-oxide

RN given refers to (3beta,5alpha,6alpha)-isomer; structure

Also Known As:

5,6-epoxycholesta-3-ol; cholestan-5 alpha,6 alpha-epoxy-3 beta-ol; cholesterol 5,6-epoxide; cholesterol alpha-epoxide; cholesterol alpha-oxide, (3beta)-isomer; cholesterol alpha-oxide, (3beta,5beta,6beta)-isomer; cholesterol alpha-oxide, 4-(14)C-labeled, (3beta,5alpha,6alpha)-isomer; cholesterol alpha-oxide, 4-(14)C-labeled, (3beta,5beta,6beta)-isomer; cholesterol epoxide; cholesterol-5 alpha,6 alpha-epoxide; cholesterol-5 alpha,6 alpha-oxide; cholesterol-5 beta,6 beta-epoxide; 5 alpha,6 alpha-epoxycholestan-3 beta-ol

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Related Diseases

1.	Endometrial Neoplasms (Endometrial Cancer) 10/01/1994 - "Endometrial cancer cases had significantly higher cholesterol-5 beta,6 beta-epoxide levels than the controls (P = 0.01). " 10/01/1994 - "Increased plasma level of cholesterol-5 beta,6 beta-epoxide in endometrial cancer patients." 10/01/1994 - "These data suggest a possible role for cholesterol-5 beta,6 beta-epoxide as a biomarker of endometrial cancer risk. "
2.	Skin Neoplasms (Skin Cancer) 01/01/1991 - "Experimental evidence indicates a relationship between cholesterol alpha-epoxide and skin cancer, and exposure of skin fibroblasts to ultraviolet radiation enduces formation of significant levels of this oxide. "
3.	Hyperplasia 01/01/1991 - "Higher than normal levels of cholesterol alpha-epoxide have been found in breast fluid aspirates of women with benign breast disease, with or without atypical hyperplasia of the epithelium, and this may be a factor in the increased incidence of breast cancer associated with hyperplasia. "
4.	Hyperlipoproteinemias 08/01/1988 - "In marked contrast to results previously reported with a less accurate method, patients with various forms of hyperlipoproteinemia did not have increased levels of cholesterol epoxide. "
5.	Colonic Neoplasms (Colon Cancer) 01/01/1978 - "Cholesterol-5 alpha, 6 alpha-epoxide has been implicated as an etiologic agent in human colon cancer. "

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