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homoharringtonine

alkaloid from Cephalotaxus harringtonia; RN given refers to (3(R))-isomer; FDA approved orphan drug status for Ceflatonin in the treatment of chronic myeloid leukemia due to being an inducer of apoptosis in myeloid cells and inhibitor of angiogenesis
Also Known As:
Ceflatonin; homoharringtonine, 3H-labeled, (3(R))-isomer; omacetaxine mepesuccinate
Networked: 172 relevant articles (17 outcomes, 43 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Cortes, Jorge: 10 articles (01/2015 - 04/2002)
2. Jin, Jie: 8 articles (10/2013 - 07/2007)
3. Wetzler, Meir: 6 articles (05/2015 - 01/2011)
4. Kantarjian, H M: 5 articles (01/2015 - 10/2000)
5. Kantarjian, Hagop: 5 articles (01/2015 - 01/2007)
6. Tong, Yin: 5 articles (01/2014 - 01/2008)
7. Qian, Wen-bin: 5 articles (10/2013 - 11/2009)
8. Quintás-Cardama, Alfonso: 5 articles (10/2013 - 01/2007)
9. Kantarjian, Hagop M: 4 articles (05/2015 - 04/2002)
10. Baccarani, Michele: 4 articles (05/2015 - 07/2013)

Related Diseases

1. BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
2. Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
3. Acute Promyelocytic Leukemia
4. Leukemia
5. Neoplasms (Cancer)

Related Drugs and Biologics

1. Cytarabine (Cytosar-U)
2. Daunorubicin (Cerubidine)
3. homoharringtonine
4. Granulocyte Colony-Stimulating Factor (G-CSF)
5. Aclarubicin
6. imatinib (Gleevec)
7. Esters
8. Tretinoin (Retinoic Acid)
9. silvestrol
10. cephalotaxine

Related Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Salvage Therapy
3. Intravenous Injections
4. Aftercare (After-Treatment)
5. Stents