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hemichrome

heme protein

Also Known As:

haemichrome

Networked: 8 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Hemeproteins: 194
    - hemichrome: 8

Experts

1.	Atipimonpat, Anyapat: 1 article (08/2021)
2.	Khowawisetsut, Ladawan: 1 article (08/2021)
3.	Khuhapinant, Archrob: 1 article (08/2021)
4.	Pattanapanyasat, Kovit: 1 article (08/2021)
5.	Siwaponanan, Panjaree: 1 article (08/2021)
6.	Sukapirom, Kasama: 1 article (08/2021)
7.	Svasti, Saovaros: 1 article (08/2021)

Related Diseases

1.	Sickle Cell Anemia (Hemoglobin S Disease) 11/15/1993 - "To further define the nature of abnormal iron deposits on the membranes of pathologic red blood cells, we have used sickle cell anemia (HbSS), HbSC, and beta-thalassemic erythrocytes (RBCs) to prepare inside-out membranes (IOM) and insoluble membrane aggregates (AGGs) containing coclustered hemichrome and band 3. Study of IOM from HbSC and thalassemic patients showed that amounts of heme iron and, especially, free iron were much higher in patients who had undergone surgical splenectomy. "
2.	Thalassemia 09/01/1995 - "Hemichrome binding to band 3, hemichrome-mediated oxidation of band-3 cytoplasmic domains, generation of high-molecular-weight band-3 aggregates, and enhanced opsonization by anti-band-3 antibodies is a possible sequence of events leading to phagocytic removal of erythrocytes in thalassemia." 08/01/2021 - "Extracellular vesicles from thalassemia patients carry iron-containing ferritin and hemichrome that promote cardiac cell proliferation."
3.	Dehydration (Water Stress) 12/01/1990 - "A one-cycle dehydration of bovine hemoglobin followed by solubilization shows 100% reversibility of hemichrome P. " 05/01/1990 - "The equilibrium and kinetics of methemoglobin conversion to hemichrome induced by dehydration were investigated by visible absorption spectroscopy. "
4.	Iron Overload 01/15/1998 - "These results suggest that total OHP is more sensitive than hemichrome formation as an indicator of oxidative stress in this in vivo model of iron overload."
5.	beta-Thalassemia (Cooley's Anemia) 09/01/1995 - "Role of hemichrome binding to erythrocyte membrane in the generation of band-3 alterations in beta-thalassemia intermedia erythrocytes."

Related Drugs and Biologics

1.	Iron
2.	Heme (Haem)
3.	Methemoglobin
4.	Indicators and Reagents (Reagents)
5.	Histidine (L-Histidine)
6.	Hemoglobins (Hemoglobin)
7.	Ferritins (Ferritin)
8.	Cysteine (L-Cysteine)
9.	Antibodies

Related Therapies and Procedures

1.	Splenectomy