|1.||Kopp, Brigitte: 2 articles (06/2013 - 01/2013)|
|2.||Zehl, Martin: 2 articles (06/2013 - 01/2013)|
|3.||Kiss, Robert: 2 articles (06/2013 - 01/2013)|
|4.||Urban, Ernst: 2 articles (06/2013 - 01/2013)|
|5.||Moreno Y Banuls, Laetitia: 2 articles (06/2013 - 01/2013)|
|6.||Bai, Liang-Liang: 1 article (08/2014)|
|7.||Zhang, Dong-Mei: 1 article (08/2014)|
|8.||Peng, Qun-Long: 1 article (08/2014)|
|9.||Li, Yong: 1 article (08/2014)|
|10.||Deng, Li-Juan: 1 article (08/2014)|
|1.||Liver Neoplasms (Liver Cancer)
08/05/2014 - "In summary, our study is the first to report the efficacy of hellebrigenin against HepG2 and elucidated its molecular mechanisms including DNA damage, mitochondria collapse, cell cycle arrest and apoptosis, which will contribute to the development of hellebrigenin into a chemotherapeutic agent in the treatment of liver cancer. "
06/28/2013 - "In addition, all genins and degradation products displayed weaker (if any) in vitro growth inhibitory effects on cancer cells when compared to their respective glycosylated homologue, with the exception of hellebrigenin (3b), which was as active as hellebrin (3a). "
12/01/1969 - "The isolation and characterization of hellebrigenin 3-acetate and hellebrigenin 3,5-diacetate, bufadienolide tumor inhibitors from Bersama abyssinica."
01/01/1968 - "The isolation and characterization of hellebrigenin 3-acetate and hellebrigenin 3,5-diacetate, bufadienolide tumor inhibitors from Bersama abyssinica."
01/01/2013 - "Hellebrin and its aglycone form hellebrigenin display similar in vitro growth inhibitory effects in cancer cells and binding profiles to the alpha subunits of the Na+/K+-ATPase."
01/01/2013 - "Altogether, these data show that the binding affinity of the bufadienolides and cardenolides under study is usually higher for the α2β1 and α3β1 than for the α1β1 NaK complex, excepted for hellebrin and its aglycone form, hellebrigenin, with hellebrigenin being as potent as hellebrin in inhibiting in vitro cancer cell growth."
|3.||Hepatocellular Carcinoma (Hepatoma)
08/05/2014 - "Hellebrigenin induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells through inhibition of Akt."
08/05/2014 - "In searching for natural constituents with anti-hepatoma activities, we found that hellebrigenin, isolated from traditional Chinese medicine Venenum Bufonis, potently reduced the viability and colony formation of human hepatocellular carcinoma cells HepG2, and went on to explore the underlying molecular mechanisms. "
|5.||Adenosine Triphosphatases (ATPase)
|1.||Chinese Traditional Medicine (Traditional Chinese Medicine)