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2,2'-dipyridyl disulfide

disulfide is an important moiety in this cpd

Also Known As:

2,2'-dithiodipyridine; 2,2'-dithiopyridine; 2,2-PDS; 2,2-dithiobispyridine; Aldrithiol-2; orthopyridyl disulfide

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Camerini, David: 1 article (09/2006)
2.	Choudhary, Shailesh K: 1 article (09/2006)
3.	Planelles, Vicente: 1 article (09/2006)
4.	Powell, Douglas M: 1 article (09/2006)
5.	Walker, Russell M: 1 article (09/2006)
6.	Walsh, Craig: 1 article (09/2006)
7.	Chang, Hong-Tai: 1 article (02/2003)
8.	Chen, Wei-Chung: 1 article (02/2003)
9.	Huang, Jong-Khing: 1 article (02/2003)
10.	Jan, Chung-Ren: 1 article (02/2003)

Related Diseases

1.	Osteosarcoma (Osteogenic Sarcoma) 02/28/2003 - "2,2'-dithiodipyridine (2,2'-DTDP), a reactive disulphide that mobilizes Ca(2+) in muscle, induced an increase in cytoplasmic free Ca(2+)concentrations ([Ca(2+)](i)) in MG63 human osteosarcoma cells loaded with the Ca(2+)-sensitive dye fura-2. " 02/28/2003 - "Thiol oxidation by 2,2'-dithiodipyridine induced calcium mobilization in MG63 human osteosarcoma cells."
2.	Infections 09/01/2006 - "Here we report that HIV-1 infection induced apoptosis primarily in productively infected thymocytes; aldrithiol-2 or Efavirenz treatment largely abrogated HIV-1-induced apoptosis. "
3.	Contracture 01/01/1978 - "Coenzyme dependent suppression of 2,2-PDS induced contractures in Spirostomum."
4.	Ehrlich Tumor Carcinoma 11/01/1968 - "Restoration of glycolysis and respiration in Ehrlich ascites tumor cells inhibited by 2,2'-dithiodipyridine."
5.	Ascites 12/01/1967 - "The effect of 2,2'-dithiodipyridine on thiols and oxidizable substrates of Ehrlich ascites cells and of normal mouse tissues."

Related Drugs and Biologics

1.	Sulfhydryl Compounds (Thiols)
2.	Fura-2 (Fura 2)
3.	Coloring Agents (Dyes)
4.	Coenzymes (Enzyme Cofactors)
5.	Calcium
6.	efavirenz (Sustiva)