depsidone

a dibenzo dioxepin with a lactone formed by one of the oxygens and a carbonyl between the two benzyl rings; some derivatives are found in GARCINIA plants

Also Known As:

Networked: 3 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Cardile, V: 2 articles (02/2017 - 01/2012)
2.	Piovano, M: 2 articles (02/2017 - 01/2012)
3.	Russo, A: 2 articles (02/2017 - 01/2012)
4.	Avola, R: 1 article (02/2017)
5.	Graziano, A C E: 1 article (02/2017)
6.	Akl, Mohamed R: 1 article (04/2016)
7.	Bhattacharjee, Joydeep: 1 article (04/2016)
8.	Ebrahim, Hassan Y: 1 article (04/2016)
9.	Egbert, Susan: 1 article (04/2016)
10.	El Sayed, Khalid A: 1 article (04/2016)

Related Diseases

1.	Prostatic Neoplasms (Prostate Cancer) 01/05/2012 - "With the aim of identifying novel agents with antigrowth and pro-apoptotic activity on prostate cancer cells, in the present study, we evaluated the effect of five lichen secondary metabolites the depsides atranorin (1), diffrattaic (2) and divaricatic (3) acids, the depsidone vicanicin (4) and the protolichesterinic acid (5) on cell growth in androgen-sensitive (LNCaP) and androgen-insensitive (DU-145) human prostate cancer cells. "
2.	Melanoma (Melanoma, Malignant) 02/01/2017 - "Although the molecular mechanism, by which apoptosis is induced by physodic acid remains unclear, and of course further studies are needed, the results here reported confirm the promising biological properties of depsidone compounds, and may offer a further impulse to the development of analogues with more powerful efficiency against melanoma cells."
3.	Breast Neoplasms (Breast Cancer) 04/01/2016 - "The anticancer-guided fractionation of Usnea strigosa (Ach.) lichen extract led to the identification of the depsidone-derived norstictic acid as a novel bioactive hit against breast cancer cell lines. "

Related Drugs and Biologics

1.	Depsides
2.	Androgens
3.	Acids
4.	vicanicin
5.	protolichesterinic acid
6.	physodic acid
7.	atranorin
8.	norstictic acid