securinine

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9 relevant articles (0 outcomes, 1 trials/studies) found for this Bio-Agent

Description: a pseudoalkaloid (not from amino acid) from Securinega suffurutiosa or Securinini nitras; RN given refers to parent cpd

Also Known As:

allonorsecurinine; securinan-11-one; securinine methiodide; securinine nitrate; (6S,11aR,11bS)-9,10,11,11a-Tetrahydro-8H-6,11b-methanofuro(2,3-c)pyrido(1,2-a)azepin-2(6H)-one

Bio-Agent Context: Research Results

Heterocyclic Compounds: 23

Alkaloids: 633

securinine: 9

1-Ring Heterocyclic Compounds

Heterocyclic Compounds with 4 or More Rings

securinine: 9

Organic Chemicals: 40

Lactones: 133

securinine: 9

Related Diseases

1.	Leukemia 03/01/1999 - "AIM: To study whether securinine might induce apoptosis in human leukemia HL-60 cells" 03/01/1999 - "Securinine induced apoptosis in human leukemia HL-60 cells." Get all the results and reference details, order at left...
2.	Aplastic Anemia (Anemia, Hypoplastic) 12/01/1983 - "Treatment of chronic aplastic anemia with securinine--analysis of 123 cases]" 11/01/1984 - "Effect of combined therapy with securinine and stanozolol in patients with chronic aplastic anemia]" Get all the results and reference details, order at left...
3.	Motor Neuron Disease (Primary Lateral Sclerosis) 01/01/1973 - "From Asia securinine--a central nervous stimulant is used in treatment of amytrophic lateral sclerosis." Get all the results and reference details, order at left...
4.	Seizures (Seizure) 03/18/1985 - "All of these compounds induced tonic seizures in mice, with CD50 values ranging from 11 to 87 mg/kg. The CD50 for bicuculline was found to be 8 mg/kg. Equilibrium binding assays revealed that securinine and dihydrosecurinine inhibit [3H]GABA binding to rat brain membranes with an IC50 of approximately 50 microM, which is some 7 times less potent than bicuculline" Get all the results and reference details, order at left...
5.	Poliomyelitis (Polio) 09/01/1958 - "Result of application of securinine in acute poliomyelitis.]" Get all the results and reference details, order at left...
8 Diseases and 9 more articles analyzed in the Research Interface, order at left...

Related Drugs and Biologics

1.	Vitamin B 12 (Cyanocobalamin)
2.	Thiamine (Aneurin)
3.	Strychnine
4.	Stanozolol (Winstrol)
5.	Neostigmine (Neostigmine Bromide)
6.	gamma-Aminobutyric Acid (GABA)
7.	Bicuculline
8.	bendazole
8 Drugs and Important Bio-Agents and 3 more articles analyzed in the Research Interface, order at left...

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