|1.||McDermott, John: 3 articles (09/2004 - 04/2003)|
|2.||Clausen, Peter-Henning: 3 articles (09/2004 - 04/2003)|
|3.||Marcotty, Tanguy: 2 articles (12/2012 - 01/2010)|
|4.||Sidibe, Issa: 2 articles (12/2012 - 09/2004)|
|5.||Delespaux, Vincent: 2 articles (12/2012 - 01/2010)|
|6.||Vitouley, Hervé Sèna: 2 articles (12/2012 - 01/2010)|
|7.||Tettey, J N A: 2 articles (01/2008 - 12/2006)|
|8.||Watson, D G: 2 articles (12/2006 - 12/2002)|
|9.||Skellern, G G: 2 articles (12/2006 - 12/2002)|
|10.||Boibessot, I: 2 articles (12/2006 - 12/2002)|
12/01/2009 - "evansi infection significantly decreased haematological values, however Isometamidium treatment significantly (P < 0.05) improved Hb and PCV without any significant changes in TEC and TLC values. "
03/01/1987 - "A similar result was obtained with samorin at 0.1 microgram/ml. Subsequent experiments showed that administration of both drugs at an early stage was more effective in preventing the maturation of infection than a later but more prolonged administration. "
04/01/1991 - "Thus, although intravenous administration of isometamidium eliminated a fully sensitive infection, treatment by this route appeared not to enhance the therapeutic efficacy of the drug in the treatment of a T. "
04/01/1991 - "Infections in cattle with this clone were eliminated by intravenous treatment with 0.25 mg kg-1 isometamidium chloride or intramuscular treatment with 0.5 mg kg-1 isometamidium chloride. "
02/01/1991 - "Eleven days after infection all animals were treated with 0.5 mg kg-1 isometamidium chloride and all were cured. "
|2.||Body Weight (Weight, Body)
03/25/2008 - "ISMM at doses 0.5-4 mg/kg body weight (bw) and DA at doses of 3.5-28 mg/kg bw failed completely to cure T. "
04/01/2004 - "Fourteen days later (day 0), the 50 treatment cattle were given isometamidium chloride at 1 mg/kg body weight. "
10/02/2000 - "Fifty parasitaemic cattle from two villages were treated with isometainidium chloride (Trypamidium(R)) at a prophylactic dose of 1.0 mg/kg body weight (b.w.) and thereafter monitored on a monthly basis for parasitaemia. "
05/01/1998 - "The first group (n = 42) was treated with ISMM at a dose of 1 mg/kg of body weight, the second group (n = 44) received the same dose of the drug via an SRD, which was subcutaneously implanted in the shoulder region, and the third group (n = 36) was kept as an untreated control group. "
09/15/1997 - "In mice the 50% curative doses (CD50) for Samorin range from 0.007 to 20 mg/kg body weight. "
01/07/2008 - "Isometamidium, a mixture of related substances of which 8-(3-m-amidinophenyl-2-triazeno)-3-amino-5-ethyl-6-phenylphenanthridinium chloride hydrochloride (M&B4180A) is the principal active component, is the only chemical agent available for prophylaxis of veterinary trypanosomiasis. "
12/01/2006 - "Little is known about the metabolism and mechanism of action of the trypanocide, isometamidium (ISM), the major drug used for prophylaxis of trypanosomiasis. "
05/01/1998 - "Statistical analysis showed that the incidence of trypanosomiasis was significantly lower (P = 0.006) in the group which received ISMM via the SRD than in the one which was treated with ISMM intramuscularly."
05/01/1998 - "Field evaluation of the prophylactic effect of an isometamidium sustained-release device against trypanosomiasis in cattle."
02/01/1992 - "Two methods of trypanosome control in Boran cattle kept under very high trypanosomiasis risk were compared: the traditional intramuscular isometamidium chloride prophylaxis with a parasite detection and intravenous isometamidium chloride treatment method. "
02/01/1992 - "When isometamidium chloride at 1 mg/kg was used, the curative intravenous method appeared to be superior to the intramuscular prophylaxis with regard to cost of drugs and to a 31% higher weight gain over a 30 week period. "
04/01/1973 - "[Effect of Samorin injections on weight gain and milk supply in the West African Zebu-Azaouak cattle]."
02/01/1984 - "The results indicate that, even though the direct costs for drugs under the two maintenance regimens were almost identical, the use of Trypamidium resulted in a significantly greater annual weight gain, prevented death loss due to trypanosomiasis and resulted in a herd with a greater market value."
06/01/1992 - "The surviving animals in the isometamidium chloride herd had a mean annual weight gain of 24 kg less than that recorded in the homidium bromide herd."
02/01/1989 - "Notes on the routine intravenous use of isometamidium in the control of bovine trypanosomiasis on the Kenya coast."
02/01/1970 - "Bovine trypanosomiasis--control with 'Samorin'."
09/01/1988 - "The paper calls for judicious use of Berenil and Samorin, as they are the only sanative pairs available for the chemotherapy of bovine trypanosomiasis."
06/01/1993 - "The control of bovine trypanosomiasis in Africa continues to rely heavily on the chemoprophylactic drug isometamidium (ISMM) chloride. "
05/15/1993 - "Isometamidium chloride (Samorin) is the only compound recommended for prophylaxis against bovine trypanosomiasis in sub-Saharan Africa. "
|1.||isometamidium chloride (ISMM)
|3.||Ethidium (Ethidium Bromide)
|4.||Dihydrotachysterol (AT 10)
|7.||Suramin (Suramin Sodium)
|9.||Melarsoprol (Mel B)