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bumecain
RN given refers to parent cpd; structure
Also Known As:
N-butyl-alpha-pyrrolidine carbonic acid mesidine; bumecain hydrochloride; pirromecaine; pyromecaine; pyromecaine-collagen; pyrromecain; 1-butyl-2',4',6'-trimethyl-2-pyrrolidinecarboxanilide
Networked:
5
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Pyrrolidines: 115
bumecain: 5
Related Diseases
1.
Cardiac Arrhythmias (Arrythmia)
04/01/1985 - "
[Pyromecaine--a new anti-arrhythmia preparation improving myocardial blood supply].
"
09/01/1983 - "
[Anti-arrhythmia properties of pyromecaine].
"
04/01/1985 - "
Its marked antiarrhythmic activity has been established in various models of experimental cardiac arrhythmia in doses of 0.1-2.5 mg/kg. Pyromecaine has a wide spectrum of antiarrhythmic action, exerts a favourable effect on the intracardiac and systemic hemodynamics, on the contractility of the left ventricle and on the myocardial blood flow following the ligation of the coronary artery.
"
2.
Ganglion Cysts (Ganglion)
11/01/1985 - "
The experiments on the isolated neurons in the rat spinal ganglions have shown that interaction of pyromecaine with inactivated Na+ channels makes a considerable contribution to the blocking effect of anesthesia.
"
11/01/1985 - "
The effects of the local anesthetic pyromecaine on the action potential parameters of the guinea-pig heart ventricular cardiomyocytes as well as on Na and K ionic currents of the neurons in the rat spinal ganglions have been studied.
"
3.
Myocardial Ischemia (Ischemic Heart Diseases)
01/01/1990 - "
The treatment with pyromecaine and pyrroxan for 5 days was found to prevent disturbances of the physicochemical properties and the composition of the components of actomyosin complex of the rat heart left ventricle caused by experimental myocardial ischemia.
"
4.
Necrosis
02/01/1986 - "
The experiments on rats with a 3-day myocardial infarction caused by the left coronary artery ligation have shown that multiple lidocaine and pyromecaine injections according to a given scheme decrease the size of the necrosis area.
"
5.
Myocardial Infarction
02/01/1986 - "
[Effect of lidocaine and pyromecaine on the size of an experimental myocardial infarct].
"
02/01/1986 - "
The experiments on rats with a 3-day myocardial infarction caused by the left coronary artery ligation have shown that multiple lidocaine and pyromecaine injections according to a given scheme decrease the size of the necrosis area.
"
Related Drugs and Biologics
1.
Lidocaine (Xylocaine)
2.
Local Anesthetics
3.
Actomyosin
4.
proroxan
Related Therapies and Procedures
1.
Ligation
2.
Injections
3.
Anesthesia