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LSP2-9166

a mixed mGlu4-mGlu7 receptor orthosteric agonist

Also Known As:

((2S)-2-amino-4-(((4-(carboxymethoxy)-3-(trifluoromethoxy)phenyl)(hydroxy)methyl)(hydroxy)phosphoryl)butanoic acid

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Acyclic Acids
    - Butyrates: 2613
      - Aminobutyrates: 1253
        LSP2-9166: 1
Amino Acids, Peptides, and Proteins: 1
- Amino Acids: 30675
  - Aminobutyrates: 1253
    - LSP2-9166: 1

Experts

1.	Acher, Francine: 1 article (01/2019)
2.	Barboux, Cedric: 1 article (01/2019)
3.	Bertaso, Federica: 1 article (01/2019)
4.	Bouschet, Tristan: 1 article (01/2019)
5.	Dairou, Julien: 1 article (01/2019)
6.	Fagni, Laurent: 1 article (01/2019)
7.	Girard, Benoit: 1 article (01/2019)
8.	Marchi, Nicola: 1 article (01/2019)
9.	McCort-Tranchepain, Isabelle: 1 article (01/2019)
10.	Moreno, Maria Paula: 1 article (01/2019)

Related Diseases

1.	Seizures (Absence Seizure) 01/01/2019 - "LSP2-9166 also acts as an anti-seizure drug on established seizures in both models tested. "
2.	Temporal Lobe Epilepsy 01/01/2019 - "In the intra-hippocampal injection of kainic acid mouse model that mimics the human mesial temporal lobe epilepsy, we found that LSP2-9166 reduces seizure frequency and hippocampal sclerosis. "
3.	Hippocampal Sclerosis 01/01/2019 - "In the intra-hippocampal injection of kainic acid mouse model that mimics the human mesial temporal lobe epilepsy, we found that LSP2-9166 reduces seizure frequency and hippocampal sclerosis. "

Related Drugs and Biologics

1.	Kainic Acid (Kainate)