anthricin

antitumor constituent from Anthriscus sylvestris (L.) Hoffm; structure in first source

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

1.	Colorectal Neoplasms (Colorectal Cancer) 10/02/2015 - "These results suggest that the methanol extract and anthricin derived from CO leaves might be useful in the development of medicines with anti-colorectal cancer activity. "
2.	Neoplasms (Cancer) 06/01/2018 - "Anthricin significantly inhibited tumor growth without any significant change in the body weight of mice in A549 tumor xenograft BALB/c nude mice. "
3.	Lung Neoplasms (Lung Cancer) 06/01/2018 - "However, the anticancer effects of anthricin on A549 human non‑small cell lung cancer cells and potential molecular mechanisms remain unknown. "
4.	Breast Neoplasms (Breast Cancer) 01/01/2013 - "Taken together, our results indicate that anthricin is an inhibitor of mTOR and that a combination of an autophagy inhibitor and anthricin may serve as a new promising strategy for the treatment of breast cancer cells. " 01/01/2013 - "Here, we investigated the effect of anthricin on autophagy and mammalian target of rapamycin (mTOR) signaling as anticancer actions in breast cancer cells. " 01/01/2013 - "Our data confirmed that anthricin markedly induced apoptosis in 2 breast cancer cell lines, MCF7 (estrogen receptor positive) and MDA-MB-231 (estrogen receptor, progesterone receptor, and Her2/Neu receptor negative). "
5.	Body Weight (Weight, Body) 06/01/2018 - "Anthricin significantly inhibited tumor growth without any significant change in the body weight of mice in A549 tumor xenograft BALB/c nude mice. "

1.	TOR Serine-Threonine Kinases
2.	ErbB-2 Receptor
3.	Progesterone Receptors (Progesterone Receptor)
4.	Estrogen Receptors
5.	Methanol (Carbinol)