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cornin iridoid

structure

Also Known As:

verbenalin

Networked: 11 relevant articles (1 outcomes, 5 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Miao, Mingsan: 2 articles (09/2018 - 01/2016)
2.	Chen, Jun: 1 article (06/2020)
3.	Lu, Hongzhou: 1 article (06/2020)
4.	Su, Jie: 1 article (06/2020)
5.	Tao, Zhengang: 1 article (06/2020)
6.	Wong, Catherine C L: 1 article (06/2020)
7.	Wu, Shifei: 1 article (06/2020)
8.	Yao, Hebing: 1 article (06/2020)
9.	Yuang, Ying: 1 article (06/2020)
10.	Ferdousi, Farhana: 1 article (01/2020)

Related Diseases

1.	Infections 06/30/2020 - "Three compounds (forsythoside E, verbenalin, and emodin) exert the advantages of protective effects in cell vitality during H1N1 infection. "
2.	Neuroblastoma 01/01/2023 - "These results indicated that verbenalin and (+)-eudesmin exert potent cytoprotective activities against cytotoxicity triggered by 6-OHDA in neuroblastoma cells. " 01/01/2020 - "Additionally, the neuroprotective effect of verbenalin was confirmed against amyloid beta-induced neurotoxicity in human neuroblastoma SH-SY5Y cells. " 01/01/2023 - "The purpose of this research was to study whether verbenalin, an iridoid glucoside, and (+)-eudesmin, a furofuran lignan isolated from different plant families, can attenuate cell damage and death induced by 6-hydroxydopamine (6-OHDA) in human neuroblastoma SH-SY5Y cells. "
3.	Alzheimer Disease (Alzheimer's Disease) 01/01/2020 - "Microarray analysis of verbenalin-treated human amniotic epithelial cells reveals therapeutic potential for Alzheimer's Disease." 12/08/2022 - "Verbenalin Reduces Amyloid-Beta Peptide Generation in Cellular and Animal Models of Alzheimer's Disease." 12/08/2022 - "This study demonstrates the effects of verbenalin on amyloid-beta (Aβ) peptide generation in Swedish mutant amyloid precursor protein (APP)-overexpressing Neuro2a cells (SweAPP/N2a) and in Alzheimer's disease (AD) animal models. "
4.	Lung Injury 01/01/2023 - "In this study, we demonstrate the therapeutic effect of verbenalin on lung injury through direct binding to the GPR18 receptor. "
5.	Mitochondrial Diseases (Mitochondrial Disease) 05/10/2023 - "Verbenalin attenuates hepatic damage and mitochondrial dysfunction in alcohol-associated steatohepatitis by regulating MDMX/PPARα-mediated ferroptosis." 05/10/2023 - "To elucidate the molecular mechanism by which verbenalin inhibits abnormal mitochondrial dysfunction, molecular docking was performed, and MDMX was identified as the target protein of verbenalin. " 05/10/2023 - "To study the effects of verbenalin on the prevention of alcoholic steatohepatitis (ASH) through the regulation of oxidative stress and mitochondrial dysfunction by regulating MDMX (Murine double minute X)/PPARα (Peroxisome proliferator-activated receptor alpha)-mediated ferroptosis. "

Related Drugs and Biologics

1.	Emodin (Archin)
2.	Proteins (Proteins, Gene)
3.	Therapeutic Uses
4.	Amyloid beta-Peptides
5.	Iridoid Glucosides
6.	PPAR alpha
7.	Lignans
8.	Oxidopamine (6 Hydroxydopamine)
9.	Peptides (Polypeptides)
10.	Amyloid (Amyloid Fibrils)