antifungal metabolite from Cladosporium cladosporioides; toxic, minor metabolite of Aspersillus flavus
Also Known As:
3,4-dihydro-6,8-dihydroxy-3-(6-methyltetrahydropyran- 2-ylmethyl)isocoumarin; asperentin; 3,4-dihydro-6,8-dihydroxy-3-(tetrahydro-6- methyl-2H-pyran-2-yl)methylisocoumarin
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Bio-Agent Context: Research Results
- "Transcriptional responses of 13 inflammation/respiratory burst-associated genes (KC=Cxcl1, Cxcl2, Cxcl5, Cxcl10, Ccl3, Ccl112, Ccl20, IL-1β, Il-6, ifi27 Tnfα, iNOS and Blvrb) were evaluated in mouse AMs exposed to a 1ml (10(-8)mol) dose of either pure atranone C, brevianimide, cladosporin, curdlan, LPS, neoechinulin A & B, sterigmatocystin or TMC-120A for 2h, 4h and 12h PE using customized reverse transcription (RT)-PCR based arrays.
|3. ||Carcinoma (Carcinomatosis)
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