S-2-aminoethyl cysteine

inhibits protein synthesis in mammalian cells; RN given refers to parent cpd; structure

Also Known As:

4-thia-L-lysine; 4-thialysine; S-2-aminoethyl cysteine dihydrochloride; S-2-aminoethyl cysteine hydrochloride; S-2-aminoethyl cysteine monohydrochloride; S-beta-aminoethyl cysteine; aminoethylcysteine; gamma-thia-Lys; gamma-thialysine; thialysine; thiosine; S-(2-aminoethyl)-L-cysteine

Networked: 7 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Pathania, Amit: 1 article (06/2015)
2.	Sardesai, Abhijit A: 1 article (06/2015)
3.	Pegg, Anthony E: 1 article (06/2008)
4.	Bae, Young Seuk: 1 article (12/2003)
5.	Han, Kyu Hyun: 1 article (12/2003)
6.	Jun, Do Youn: 1 article (12/2003)
7.	Kim, Young Ho: 1 article (12/2003)
8.	Lee, Young Sup: 1 article (12/2003)
9.	Rue, Seok Woo: 1 article (12/2003)
10.	Taub, Dennis: 1 article (12/2003)

Related Diseases

1.	Amyloidosis 02/01/1986 - "A morphologic study of 376 hearts from individuals who died between 75 and 98 years of age demonstrated senile amyloidosis of the heart in 307 (82%) of the cases, using the Congo red stains for polarized light studies and the thiosine red for luminescent microscopy. "
2.	Weight Loss (Weight Reduction) 08/01/1981 - "Analogous substitution of D-lysine and the lysine sulfur-containing analog, S-(2-aminoethyl)-L-cysteine, for lysine resulted in weight losses during the feeding period. "
3.	Lyme Disease (Disease, Lyme) 11/25/2003 - "In vivo inhibition by S-(2-aminoethyl)-L-cysteine was investigated by replacing the endogenous LysRS2 of Bacillus subtilis with LysRS1 from the Lyme disease pathogen Borrelia burgdorferi. "
4.	Leukemia 12/15/2003 - "We first report the mechanism for the inhibitory effect of the lysine analog, thialysine on human acute leukemia Jurkat T cells. " 12/15/2003 - "Mechanism underlying cytotoxicity of thialysine, lysine analog, toward human acute leukemia Jurkat T cells."
5.	Hypersensitivity (Allergy) 06/15/2015 - "The absence of YbjE did not confer a CAN(ss) phenotype but instead conferred hypersensitivity to the lysine antimetabolite thialysine and led to growth inhibition by the dipeptide lysylalanine, which is associated with elevated cellular Lys content. "

Related Drugs and Biologics

1.	Congo Red
2.	Lysine (L-Lysine)
3.	NF-kappa B (NF-kB)
4.	Sulfur
5.	Proteins (Proteins, Gene)
6.	Dipeptides
7.	Cystathionine
8.	Antimetabolites
9.	Acetyltransferases
10.	1,4-thiomorpholine-3-carboxylic acid