alachlor

01/01/2018 - "We evaluated alachlor use and cancer incidence in the Agricultural Health Study, updating an earlier analysis that suggested associations with lymphohematopoietic cancers with an additional 540 142 person-years of follow-up and 5113 cancer cases. "
01/01/2018 - "Experimental animal studies show that alachlor causes tumors in vivo; however, few epidemiologic studies have examined associations with human cancer risk. "
01/01/2018 - "Alachlor Use and Cancer Incidence in the Agricultural Health Study: An Updated Analysis."
08/01/2004 - "There were no cancers of the types found in toxicology studies and no discernible relation between cancer incidence for any site and years of alachlor exposure or time since first exposure. "
02/15/2004 - "Our findings suggest a possible association between alachlor application and incidence of lymphohematopoietic cancers among applicators in the Agricultural Health Study."

11/01/2004 - "These studies extend previous observations by describing alachlor-induced olfactory mucosal changes in mice and suggest that hepatic metabolic enzyme induction may be responsible for resistance of mice to alachlor-induced olfactory carcinogenesis."
11/01/2004 - "The current studies were performed to determine whether Apc(Min/+) mice, which have activated Wnt signaling due to mutation of the second allele of Apc, would be susceptible to alachlor olfactory carcinogenesis. "
06/01/1999 - "This study suggests that target tissue bioactivation of alachlor results in the formation of one or more mutagenic metabolite(s), which may be critical in alachlor-induced nasal tumorigenesis."
01/01/2006 - "There was no increase in mutant frequency in the adjacent nasal respiratory mucosa or in liver, which are both non-target tissues for alachlor carcinogenesis. "
11/01/2004 - "Female CD-1 mice were resistant to alachlor-induced olfactory carcinogenesis. "

01/01/1978 - "[Experimental poisoning of carp fingerlings (Cyprinus carpio L.) with the herbicidal preparation, lasagrin (alachlor)]."
09/01/2008 - "Alachlor and butachlor poisonings are usually of low toxicity. "
09/01/2008 - "We retrospectively analyzed the data of human alachlor/butachlor poisoning in Taiwan. "
09/01/2008 - "Sixty-three alachlor and 70 butachlor poisoning cases were reported to the Taiwan National Poison Center during the study period. "
09/01/2008 - "Acute alachlor and butachlor herbicide poisoning."

01/01/2023 - "In this study, a high-performance liquid chromatography tandem mass spectrometry cubed (LC/MS3) method was developed and validated to quantify alachlor in human breast cancer cells (McF-7 cells). "
01/01/2005 - "Estrogen receptor positive (ER+) MCF-7 human mammary carcinoma, HepG2 (ER+) human hepatocellular carcinoma and VERO estrogen receptor negative (ER-) non-transformed monkey fibroblast cell lines were treated with alachlor and acetochlor (2-500 microg/ml) as toxic agents, and RESV (10 microM) as preventive agent. "
11/01/1999 - "Here we demonstrate that the organochlorine pesticides o, p' DDT and alachlor, like 17beta-estradiol, have the ability to suppress tumor necrosis factor alpha (TNF)-induced apoptosis in estrogen receptor (ER)-positive MCF-7 breast carcinoma cells. "

08/01/2000 - "The herbicide acetochlor, and its analogue alachlor, have similar toxicological properties, the most significant being the induction of nasal adenomas in rats in 2-year feeding studies. "